Document Detail


P-wave morphologic characteristics predict cardiovascular events in a community-dwelling population.
MedLine Citation:
PMID:  22816544     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background: There have been few reports on the relationship between P-wave characteristics and long-term cardiovascular events. Methods: A nested case-control study was conducted as part of the Jichi Medical School cohort study, which enrolled 12,490 subjects in a community-dwelling population. The mean follow-up period was 10.7 years. The P-wave characteristics of 526 patients who suffered cardiovascular events (fatal/nonfatal stroke, fatal/nonfatal myocardial infarction, and sudden death) within the follow-up period (case group) were compared with those of 1578 matched controls (control group). The P-wave morphology was classified as normal, deflected, and notched type in precordial leads. A broad P wave was defined as a maximum P-wave duration of more than 120 ms in any of the 12 leads. Results: The mean age was 64 ± 8 years and the percentage of males was 54% in both groups. A notched P wave at baseline was observed in 10.1% of the case group and 6.0% of the control group (P = 0.001). A notched P wave was a significant predictor of cardiovascular events after adjustment for covariates (odds ratio = 1.59; 95% confidence interval = 1.08-2.33). Among the patients with left ventricular hypertrophy as evaluated by the Sokolow-Lyon criteria or Cornell product criteria, there was no significant difference in cardiovascular events between those with and those without a notched P wave, but in the absence of left ventricular hypertrophy, patients with a notched P wave suffered more cardiovascular events than those without a notched P wave by each criteria. Conclusion: P-wave morphologic characteristics were effective for predicting cardiovascular events.
Authors:
Tomoyuki Kabutoya; Shizukiyo Ishikawa; Joji Ishikawa; Satoshi Hoshide; Kazuomi Kario
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc     Volume:  17     ISSN:  1542-474X     ISO Abbreviation:  Ann Noninvasive Electrocardiol     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9607443     Medline TA:  Ann Noninvasive Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  252-9     Citation Subset:  IM    
Copyright Information:
©2012, Wiley Periodicals, Inc.
Affiliation:
Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan Department of Community and Family Medicine, Jichi Medical University School of Medicine, Tochigi, Japan.
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