| Oxytocin as feeding inhibitor: maintaining homeostasis in consummatory behavior. | |
| | |
MedLine Citation:
|
PMID: 20595062 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Initial studies showed that the anorexigenic peptide oxytocin (OT) regulates gastric motility, responds to stomach distention and to elevated osmolality, and blocks consumption of toxic foods. Most recently, it has been proposed to act as a mediator of general and carbohydrate-specific satiety and regulator of body weight. In the current review, we discuss the function of OT as a homeostatic inhibitor of consumption, capable of mitigating multiple aspects of ingestive behavior and energy metabolism. |
| | |
Authors:
|
Pawel K Olszewski; Anica Klockars; Helgi B Schiöth; Allen S Levine |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2010-06-02 |
Journal Detail:
|
Title: Pharmacology, biochemistry, and behavior Volume: 97 ISSN: 1873-5177 ISO Abbreviation: Pharmacol. Biochem. Behav. Publication Date: 2010 Nov |
Date Detail:
|
Created Date: 2010-10-11 Completed Date: 2011-09-15 Revised Date: 2011-11-01 |
Medline Journal Info:
|
Nlm Unique ID: 0367050 Medline TA: Pharmacol Biochem Behav Country: United States |
Other Details:
|
Languages: eng Pagination: 47-54 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Minnesota Obesity Center, Department of Food Science and Nutrition, University of Minnesota, St. Paul, MN 55108, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Anorexia / chemically induced, physiopathology Consummatory Behavior / drug effects, physiology* Energy Metabolism / drug effects, physiology Feeding Behavior / drug effects, physiology* Homeostasis / drug effects, physiology* Humans Obesity / physiopathology, prevention & control Oxytocin / pharmacology, physiology* |
| Grant Support | |
ID/Acronym/Agency:
|
P30 DK050456-12/DK/NIDDK NIH HHS; R01 DA021280-03/DA/NIDA NIH HHS |
| Chemical | |
Reg. No./Substance:
|
50-56-6/Oxytocin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Microbiological study of bulls of indulgence of the 15th-16th centuries.
Next Document: P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-d...