Document Detail

Oxysterols found in opacified cornea of fish.
MedLine Citation:
PMID:  8898302     Owner:  NLM     Status:  MEDLINE    
We describe a new concept implicating oxidized cholesterol derivatives and very long-chain fatty acids as possible factors in the development of corneal opacification after death. Corneal tissues, removed from both fresh and stale fish eyes, were examined for cholesterol derivatives and fatty acids after methanolysis of lipids. Cholesta-3,5-dien-7-one, cholest-4-en-3-one, hexacosenoic acid, and hexacosenoic acid were identified via gas chromatography/mass spectrometry in opacified corneas, but not in significant amounts in fresh ones. The present study confirmed the presence of lipid hydrolysis and a peroxidation process in the opacified cornea.
J Adachi; K Hojo; T Naito; Y Tatsuno
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lipids     Volume:  31     ISSN:  0024-4201     ISO Abbreviation:  Lipids     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1997-02-04     Completed Date:  1997-02-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0060450     Medline TA:  Lipids     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1039-43     Citation Subset:  IM    
Department of Legal Medicine, Kobe University School of Medicine, Japan.
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MeSH Terms
Cornea / chemistry*
Mass Spectrometry
Sterols / analysis*
Reg. No./Substance:

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