Document Detail


Oxygen utilization in newborns at delivery.
MedLine Citation:
PMID:  20121544     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: To evaluate the arteriovenous (AV) pH difference in cord blood as a possible indicator of fetal O(2)-utilization at delivery. Furthermore to examine which maternal, fetal and obstetrical factors lead to elevated O(2)-utilization. METHODS: In this retrospective study all singleton live births, delivered within a four-month period at the University Hospital in Innsbruck, Austria, were analyzed. In total 491 deliveries were evaluated. Arterial and venous cord blood samples were collected at birth and analyzed by using a Radiometer ABL 510. RESULTS: Spontaneous deliveries showed a highly significant elevation in AV-difference (pH 0.10) as compared to cesarean sections (pH 0.05). In spontaneous births, the AV-difference was high in the case of low arterial cord blood pH (P<0.01), as well as in nuchal cord (P<0.01), high parity (P<0.01), very short labor (P<0.05) and elevated birth size and weight (P<0.05). CONCLUSIONS: As a result of increased fetal stress at birth, spontaneous delivery leads to higher O(2)-utilization than cesarean section, which is detectable in an elevated AV-difference. The AV-difference in combination with absolute pH-values can be used for the objective evaluation of fetal O(2)-utilization and consecutively the fetal stress at birth.
Authors:
Andreas Gschliesser; Matthias Scheier; Hans Peter Colvin; Verena Barbieri; Anton Bergant
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  38     ISSN:  1619-3997     ISO Abbreviation:  J Perinat Med     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-04     Completed Date:  2010-06-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  203-7     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Medical University Innsbruck, Innsbruck, Austria. andreas.gschliesser@i-med.ac.at
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MeSH Terms
Descriptor/Qualifier:
Apgar Score
Birth Weight / physiology
Blood Gas Analysis
Female
Fetal Blood / metabolism*
Humans
Hydrogen-Ion Concentration
Infant, Newborn / blood*
Linear Models
Oxygen / blood*
Pregnancy
Retrospective Studies
Umbilical Arteries / physiology
Umbilical Veins / physiology
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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