Document Detail

Oxygen uptakes adjusted for body composition in normal-weight and obese adolescents.
MedLine Citation:
PMID:  15044669     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To test whether resting oxygen uptake (VO(2)), submaximal VO(2), and maximal VO(2) (VO(2max)) differs between obese adolescents (n = 18; BMI > 30) and a matched normal-weight control group after adjustment for differences in fat-free mass (FFM) and fat mass (FM). RESEARCH METHODS AND PROCEDURES: FFM and FM were assessed by DXA. Resting VO(2), submaximal VO(2), and VO(2max) were measured by indirect calorimetry. RESULTS: There was no difference in resting VO(2) between groups after adjusting for FFM and FM. Submaximal VO(2) did not differ between groups after adjusting for body weight. Percentage VO(2max) and NET VO(2) (VO(2max) - resting VO(2)) were significantly higher in the obese group during submaximal exercise, however not after adjusting for body weight. VO(2max) was not significantly different between groups after adjusting for FFM. DISCUSSION: When body compositions are appropriately controlled for, resting VO(2), submaximal VO(2), and VO(2max) do not differ between obese and normal-weight adolescents. These data suggested that the higher relative VO(2) observed in obese adolescent subjects is due to their higher FM and not to an impaired VO(2max) even though they may be less physically active.
Ulf Ekelund; Paul W Franks; Nicolas J Wareham; Jan Aman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Obesity research     Volume:  12     ISSN:  1071-7323     ISO Abbreviation:  Obes. Res.     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-03-26     Completed Date:  2004-07-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9305691     Medline TA:  Obes Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  513-20     Citation Subset:  IM    
Medical Research Council Epidemiology Unit, Cambridge, United Kingdom.
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MeSH Terms
Adipose Tissue
Body Composition*
Body Weight*
Calorimetry, Indirect
Energy Metabolism
Heart Rate
Obesity / metabolism*
Oxygen Consumption*

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