Document Detail


Oxygen uptake kinetics in children and adolescents: a review.
MedLine Citation:
PMID:  19556620     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pulmonary oxygen uptake (pVO2) kinetic response at the onset of exercise provides a noninvasive window into the metabolic activity of the muscle and a valuable means of increasing our understanding of developmental muscle metabolism. However, to date only limited research has been devoted to investigating the pVO2 kinetic response during exercise in children and adolescents. From the rigorous studies that have been conducted, both age- and sex-related differences have been identified. Specifically, children display a faster exponential rise in the phase II pVO2 kinetics, which are purported to reflect the rise in muscle O2 consumption, during moderate, heavy and very heavy intensity exercise compared with adults. Furthermore, for heavy and very heavy exercise, the O2 cost of exercise is higher for the exponential phase and the magnitude of the pVO2 slow component is smaller in young children. Sex-related differences have been identified during heavy, but not moderate exercise, with prepubertal boys displaying a faster exponential phase II pVO2 kinetic response and a smaller pVO2 slow component compared with prepubertal girls. The mechanisms underlying these differences are currently poorly understood, and form the basis for future research in this area. However, it is hypothesized that an age-related modulation of the muscle phosphate feedback controllers to signal an increased rate of oxidative phosphorylation and/or altered muscle fiber type recruitment strategies have the potential to play an important role. Overall, the data support the view that at the onset of exercise children have an enhanced potential for oxidative metabolism in the myocyte compared with adults.
Authors:
Neil Armstrong; Alan R Barker
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pediatric exercise science     Volume:  21     ISSN:  0899-8493     ISO Abbreviation:  Pediatr Exerc Sci     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-06-26     Completed Date:  2009-08-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8909729     Medline TA:  Pediatr Exerc Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  130-47     Citation Subset:  IM    
Affiliation:
Childrens Health and Exercise Research Centre, School of Sport and Health Sciences, University of Exeter, Exeter, UK.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Child
Child Welfare
Exercise / physiology*
Exercise Tolerance
Female
Humans
Kinetics
Male
Oxygen Consumption / physiology*
Young Adult

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