Document Detail

'Oxygen uptake efficiency slope' in trained and untrained subjects exposed to hypoxia.
MedLine Citation:
PMID:  18329966     Owner:  NLM     Status:  MEDLINE    
We assessed the ability of the oxygen uptake efficiency slope, whether calculated on 100 and 80% of maximal exercise test duration (OUES(100) and OUES(80)), to identify the change in cardiorespiratory capacities in response to hypoxia in subjects with a broad range of V(O2 peak). Four maximal exercise tests were performed in trained (T) and untrained subjects (UT) in normoxia and at 1000, 2500 and 4500 m. The mean reductions in maximal exercise capacities at 4500 m were the same in T subjects for V(O2 peak) (-30%), OUES(80) (-26%) and OUES(100) (-26%) whereas in UT subjects only OUES(100) (-14%), but not OUES(80) (-20%), was lower compared with V(O2 peak) (-21%, p<0.05). OUES(100) and OUES(80) were correlated with V(O2 peak) and the ventilatory anaerobic threshold in both groups. Multiple regression analyses showed that V(O2 peak), OUES(100) and OUES(80) were significantly linked to O(2) arterial-venous difference. The OUES(80) could be considered as an interesting sub-maximal index of cardiorespiratory fitness in normal or hypoxemic subjects unable to reach V(O2 peak).
Pascal Mollard; Xavier Woorons; Sophie Antoine-Jonville; Luce Jutand; Jean Paul Richalet; Fabrice Favret; Aurélien Pichon
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2008-02-03
Journal Detail:
Title:  Respiratory physiology & neurobiology     Volume:  161     ISSN:  1569-9048     ISO Abbreviation:  Respir Physiol Neurobiol     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-04-28     Completed Date:  2008-07-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  101140022     Medline TA:  Respir Physiol Neurobiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  167-73     Citation Subset:  IM    
Université Paris 13, UFR SMBH, STAPS, Laboratoire Réponses Cellulaires et Fonctionnelles à l'hypoxie, UPRES EA 2363, 74 rue Marcel Cachin, 93017 Bobigny Cedex, France.
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MeSH Terms
Adaptation, Physiological
Anoxia / blood*
Cardiovascular Physiological Phenomena
Exercise / physiology*
Exercise Test
Oxygen / blood*
Oxygen Consumption / physiology*
Physical Fitness / physiology*
Reference Values
Reg. No./Substance:

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