| Oxygen-enhanced proton imaging of the human lung using T2. | |
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MedLine Citation:
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PMID: 15844155 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Magnetic susceptibility gradients caused by tissue/air interfaces lead to very short T(2)* times in the human lung. These susceptibility gradients are dependent on the magnetic susceptibility of the respiratory gas and therefore should influence T(2)* relaxation. In this work, a technique for quantitative T(2)* mapping of the human lung during one breath hold is presented. Using this method, the lung T(2)* relaxation time was measured under normoxic (room air, 21% O(2)) and hyperoxic (100% O(2)) conditions to verify this assumption. The mean T(2)* difference between room air and 100% O(2) is about 10% and contains ventilation information, since only ventilated regions contribute to signal change due to different susceptibility gradients. |
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Authors:
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Eberhard D Pracht; Johannes F T Arnold; Tungte Wang; Peter M Jakob |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 53 ISSN: 0740-3194 ISO Abbreviation: Magn Reson Med Publication Date: 2005 May |
Date Detail:
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Created Date: 2005-04-26 Completed Date: 2005-08-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: United States |
Other Details:
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Languages: eng Pagination: 1193-6 Citation Subset: IM |
Copyright Information:
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Copyright 2005 Wiley-Liss, Inc. |
Affiliation:
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Department of Experimental Physics 5, University of Würzburg, Germany. edpracht@physik.uni-wuerzburg.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Image Enhancement / methods* Lung / anatomy & histology*, physiology Magnetic Resonance Imaging / methods* Male Oxygen / administration & dosage* Pulmonary Ventilation |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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