Document Detail

Oxygen desaturation during sleep and exercise in patients with interstitial lung disease.
MedLine Citation:
PMID:  3660289     Owner:  NLM     Status:  MEDLINE    
The relations between mean and maximum fall in arterial oxygen saturation (SaO2) during sleep, hypoxaemia during moderate and maximum exercise, and lung mechanics were studied in 16 patients with interstitial lung disease. Mean and minimum SaO2 during sleep were significantly related to each other and to daytime oxygenation but not to lung mechanics. Although the maximum fall in SaO2 during sleep was similar to the fall during maximum exercise (a level seldom achieved during normal daily activities), profound hypoxaemic episodes during sleep were rare and brief and therefore contributed little to the mean SaO2. The fall in mean SaO2 during sleep was not significant and was considerably less than during moderate exercise (average 0.5 v an estimated 4.5%, p less than 0.05). It is therefore concluded that in patients with interstitial lung disease oxygen desaturation during sleep is mild and less severe than hypoxaemia during exercise.
B Midgren; L Hansson; L Eriksson; P Airikkala; D Elmqvist
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Thorax     Volume:  42     ISSN:  0040-6376     ISO Abbreviation:  Thorax     Publication Date:  1987 May 
Date Detail:
Created Date:  1987-11-10     Completed Date:  1987-11-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0417353     Medline TA:  Thorax     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  353-6     Citation Subset:  IM    
Department of Lung Medicine, University Hospital, Lund, Sweden.
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MeSH Terms
Lung / pathology,  physiopathology
Oxygen / blood*
Physical Exertion*
Pulmonary Fibrosis / blood*,  pathology,  physiopathology
Reg. No./Substance:

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