| Oxygen dependency of life-span in the nematode. | |
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MedLine Citation:
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PMID: 8102956 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. The mean and maximum life-spans of both wild type Caenorhabditis elegans and the mev-1(kn1) mutant, whose cytoplasmic superoxide dismutase activity level is about half of the wild type, were increased and decreased under low and high concentrations of oxygen, respectively. 2. The Gompertz component, a parameter of ageing rate, of the wild type was smaller under 1% oxygen than under 2% or more oxygen. Further, the Gompertz component of the mutant increased with an increase in oxygen concentration. 3. The oxygen-dependent modulation of life-span and ageing rate seems to be enhanced by a genetic defect of the mutant in antioxidant defence. |
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Authors:
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M Matsuo |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Comparative biochemistry and physiology. Comparative physiology Volume: 105 ISSN: - ISO Abbreviation: Comp. Biochem. Physiol. Comp. Physiol. Publication Date: 1993 Aug |
Date Detail:
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Created Date: 1993-09-30 Completed Date: 1993-09-30 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9441449 Medline TA: Comp Biochem Physiol Comp Physiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 653-8 Citation Subset: IM |
Affiliation:
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Tokyo Metropolitan Institute of Gerontology, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Caenorhabditis elegans / enzymology, physiology* Life Expectancy Oxygen / physiology* Superoxide Dismutase / metabolism |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen; EC 1.15.1.1/Superoxide Dismutase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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