Document Detail

Oxygen delivery during endobronchial anaesthesia: a comparison of halothane-oxygen and nitrous oxide-oxygen.
MedLine Citation:
PMID:  7158266     Owner:  NLM     Status:  MEDLINE    
Total oxygen delivery (cardiac output X arterial oxygen content) and oxygen consumption were determined in 22 patients undergoing one-lung ventilation (OLV) during thoracotomy. In 11 patients, anaesthesia was maintained with halothane-oxygen and in another 11 patients with nitrous oxide-oxygen-analgesic combination (FIO2 0.5). During OLV, oxygen delivery was greater in the halothane group and these patients tended to show a decrease in oxygen consumption compared with the patients of the nitrous oxide group. Therefore, as far as total oxygen balance (oxygen delivery/oxygen consumption) during OLV is concerned, halothane-oxygen maintenance provides a greater margin of safety than nitrous oxide-oxygen-analgesic combination. However, in spite of occasional hypoxaemic episodes, none of our patients receiving 50% nitrous oxide in oxygen showed an oxygen delivery coefficient (oxygen delivery/oxygen consumption) significantly smaller than the predicted normal value for an unanaesthetized patient. This finding may explain why this anaesthetic technique has been used without apparent harm during OLV in patients with unimpaired cardiovascular function.
M Aalto-Setälä; J Heinonen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  26     ISSN:  0001-5172     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  1982 Dec 
Date Detail:
Created Date:  1983-03-17     Completed Date:  1983-03-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  550-3     Citation Subset:  IM    
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MeSH Terms
Anesthesia / methods*
Cardiac Output
Middle Aged
Nitrous Oxide*
Oxygen / administration & dosage*,  blood
Oxygen Consumption
Respiration, Artificial / methods*
Thoracic Surgery*
Reg. No./Substance:
10024-97-2/Nitrous Oxide; 151-67-7/Halothane; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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