| Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis. | |
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MedLine Citation:
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PMID: 20798968 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Walking impairment is a ubiquitous feature of multiple sclerosis (MS) and the O(2) cost of walking might quantify this dysfunction in mild MS. This paper examined the difference in O(2) cost of walking between persons with MS who have mild disability and healthy controls and the correlation between the O(2) cost of walking and disability. Study 1 included 18 persons with mild MS and 18 controls and indicated that the O(2) cost of walking was significantly higher in MS than controls and that disability was significantly associated with the O(2) cost of slow, moderate, and fast treadmill walking. Study 2 included 24 persons with mild MS and indicated that disability was significantly correlated with O(2) cost of comfortable, fast, and slow over-ground walking. We provide evidence that the O(2) cost of walking is an indicator of walking dysfunction in mildly disabled persons with MS and should be considered in clinical research and practice. |
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Authors:
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Robert W Motl; Yoojin Suh; Deirdre Dlugonski; Madeline Weikert; Stamatis Agiovlasitis; Bo Fernhall; Myla Goldman |
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Publication Detail:
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Type: Journal Article Date: 2010-08-27 |
Journal Detail:
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Title: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology Volume: 32 ISSN: 1590-3478 ISO Abbreviation: Neurol. Sci. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-15 Completed Date: 2011-07-07 Revised Date: 2012-03-08 |
Medline Journal Info:
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Nlm Unique ID: 100959175 Medline TA: Neurol Sci Country: Italy |
Other Details:
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Languages: eng Pagination: 255-62 Citation Subset: IM |
Affiliation:
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Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., Urbana, IL 61801, USA. robmotl@illinois.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Disabled Persons Exercise Test Female Humans Male Middle Aged Multiple Sclerosis / physiopathology* Oxygen Consumption / physiology* Walking / physiology* Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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K23 NS062898-03/NS/NINDS NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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