Document Detail


Oxygen consumption in the developing chick cornea.
MedLine Citation:
PMID:  562328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Embryonic chick corneas at different stages of development were evaluated for O2 consumption. Some embryos were treated with thyroxine or thiouracil. In untreated animals, corneal QO2 (oxygen consumption/hr./mg. dry weight) decreased from 3.60 at stage 38 to 1.58 after hatching. The temperature coefficient Q10 increased from 1.55 at stage 40 to 2.03 after hatching. If O2 consumption is calculated as microliters of O2 consumed per hour per corneal pair, it increases between stage 38 (3.20) and hatched chicks (6.20) with a plateau between stages 40 and 45. Thiouracil treatment reduced O2 consumption by the cornea at stages 42 and 45, and thyroxine treatment elevated it at stage 40.
Authors:
E Masterson; H F Edelhauser
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  16     ISSN:  0146-0404     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  1977 Nov 
Date Detail:
Created Date:  1977-12-29     Completed Date:  1977-12-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1060-2     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Animals
Body Temperature / drug effects
Chick Embryo
Cornea / metabolism*
Oxygen Consumption / drug effects*
Thiouracil / pharmacology*
Thyroxine / pharmacology*
Chemical
Reg. No./Substance:
141-90-2/Thiouracil; 7488-70-2/Thyroxine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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