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Oxygen administration in the care of neonates: a double-edged sword.
MedLine Citation:
PMID:  21034610     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the use of oxygen in neonates in the past, present and future.
DATA SOURCES: The data are mainly from Pubmed with relevant published articles from the 1940s to the present with some information gathered from web searches.
STUDY SELECTION: Studies evaluating the use of oxygen in premature and term infants through history with original milestone articles included.
RESULTS: There are still many unknowns about the proper use of oxygen in preterm and term infants but many studies suggest that both liberal use (resulting in a blood oxygen saturation of greater than 94%) as well as restrictive use (resulting in a blood oxygen saturation of less than 80% - 85%) are detrimental and have long term consequences on the infant.
CONCLUSIONS: Definitive studies evaluating the appropriate concentration and duration of supplemental oxygen are ongoing and will help in the management of term and preterm infants requiring oxygen.
Authors:
Phyllis A Dennery
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chinese medical journal     Volume:  123     ISSN:  0366-6999     ISO Abbreviation:  Chin. Med. J.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-11-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7513795     Medline TA:  Chin Med J (Engl)     Country:  China    
Other Details:
Languages:  eng     Pagination:  2938-42     Citation Subset:  IM    
Affiliation:
University of Pennsylvania School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19072, USA. dennery@email.chop.edu
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