| Oxidized LDL and paraoxanase status in ischemic stroke patients. | |
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MedLine Citation:
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PMID: 19585758 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Stroke is the leading cause of mortality and long term disability among adults in industrialized countries. Oxidative stress is an independent risk actor by inducing production of oxygen free radicals in ischemic stroke. Because a relationship may be associated between ox-ldl and paraoxanase, the aim of this study was to investigate the association between ox-ldl and paraoxanase in ischemic stroke patients by determining whether ox-ldl is a useful marker for monitoring oxidative stress in ischemic stroke patients. Our study included 100 patients of ischemic stroke and 100 controls. Compared with controls ox-ldl was significantly raised in stroke patients and Paraoxanase activity was low. Our findings suggest that there is a significant association between raised plasma ox-ldl and decrease activity of Paraoxanase with age indicating that plasma ox-ldl may reflect oxidative stress in ischemic stroke patients. |
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Authors:
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Purnima Dey Sarkar; Sushree S Rautaray |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of physiology and pharmacology Volume: 52 ISSN: 0019-5499 ISO Abbreviation: Indian J. Physiol. Pharmacol. Publication Date: 2008 Oct-Dec |
Date Detail:
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Created Date: 2009-07-09 Completed Date: 2009-07-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0374707 Medline TA: Indian J Physiol Pharmacol Country: India |
Other Details:
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Languages: eng Pagination: 403-7 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, M. G. M. Medical College, Indore. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aryldialkylphosphatase / blood* Brain Ischemia / metabolism* Female Humans Lipoproteins, LDL / blood* Male Middle Aged Oxidative Stress Stroke / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Lipoproteins, LDL; 0/oxidized low density lipoprotein; EC 3.1.8.1/Aryldialkylphosphatase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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