Document Detail

Oxidative stress and myeloperoxidase levels in saliva of patients with recurrent aphthous stomatitis.
MedLine Citation:
PMID:  19193199     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Recurrent aphthous stomatitis (RAS) is the most common oral ulcerative condition affecting 5-25% of the general population. The aim of this study was to evaluate the oxidative stress parameters in saliva of patients with RAS and to investigate the relationship among these parameters in either group.
MATERIALS AND METHODS: The study involved 50 patients with RAS of whom 24 were male and 26 were female, and 25 healthy controls of whom 13 were male and 12 were female.
RESULTS: There was no statistically significant difference in the salivary total antioxidant capacity, total oxidant status, oxidative stress index levels, and myeloperoxidase activity between patients with RAS and those in the control group.
CONCLUSIONS: The results show that reactive oxygen species may not play a role in the etiology of RAS.
F Cağlayan; O Miloglu; O Altun; O Erel; A B Yilmaz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oral diseases     Volume:  14     ISSN:  1601-0825     ISO Abbreviation:  Oral Dis     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2009-02-05     Completed Date:  2009-04-01     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  9508565     Medline TA:  Oral Dis     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  700-4     Citation Subset:  D    
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MeSH Terms
Antioxidants / analysis
Coloring Agents / diagnostic use
Hydroxyl Radical / diagnostic use
Oxidants / analysis
Oxidative Stress / physiology*
Peroxidase / analysis*
Saliva / chemistry*,  enzymology
Stomatitis, Aphthous / enzymology,  metabolism*
Young Adult
Reg. No./Substance:
0/Antioxidants; 0/Coloring Agents; 0/Oxidants; 3352-57-6/Hydroxyl Radical; EC

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