| Oxidative stress and living cells. | |
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MedLine Citation:
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PMID: 8851559 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The review deals with the effects of reactive oxygen species, both radical and nonradical (e.g. hydrogen peroxide), on cells and organisms. The chemical and biochemical aspects include description of individual reactive oxygen species, chemical reactions giving rise to them, their interconversions and interactions with metals (Fe2+, Cu2+, Cu+) and other substances (scavengers, antioxidants). The biological aspects concern the specific features and locations of cellular enzyme systems involved in radical production and/or removal. Major harmful effects of the species on the molecular (protein oxidation, lipid peroxidation, damage to DNA) and cellular level (effect on signal transduction, on cell membrane functions and on gene expression) are surveyed. Methods whereby cells and organisms cope with the onslaught of these reactive species are reviewed as well as implications for plant, animal and human health. |
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Authors:
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G Gille; K Sigler |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Folia microbiologica Volume: 40 ISSN: 0015-5632 ISO Abbreviation: Folia Microbiol. (Praha) Publication Date: 1995 |
Date Detail:
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Created Date: 1996-12-10 Completed Date: 1996-12-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376757 Medline TA: Folia Microbiol (Praha) Country: CZECH REPUBLIC |
Other Details:
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Languages: eng Pagination: 131-52 Citation Subset: IM |
Affiliation:
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Institute of Botany, Bonn, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antioxidants / metabolism Cells / metabolism* Gene Expression Regulation Humans Hydrogen Peroxide / metabolism Hydroxyl Radical / metabolism Oxidative Stress / genetics, physiology* Reactive Oxygen Species / metabolism Superoxides / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Reactive Oxygen Species; 11062-77-4/Superoxides; 3352-57-6/Hydroxyl Radical; 7722-84-1/Hydrogen Peroxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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