| Oxidative stress in development: nature or nurture? | |
| | |
MedLine Citation:
|
PMID: 20656021 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
An unavoidable consequence of aerobic respiration is the generation of reactive oxygen species (ROS). These may negatively impact development. Nevertheless, a certain amount of oxidative stress is required to allow for the normal progression of embryonic and fetal growth. Alterations in placental oxidative stress results in altered placental function and ultimately altered fetal growth and/or developmental programming leading to long-term consequences into adulthood. This article reviews the role of redox in fetal development and will focus on how developmental programming is influenced by the fetal and placental redox state as well as discuss potential therapeutic interventions. |
| | |
Authors:
|
Phyllis A Dennery |
Publication Detail:
|
Type: Journal Article Date: 2010-07-23 |
Journal Detail:
|
Title: Free radical biology & medicine Volume: 49 ISSN: 1873-4596 ISO Abbreviation: Free Radic. Biol. Med. Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-08-30 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8709159 Medline TA: Free Radic Biol Med Country: United States |
Other Details:
|
Languages: eng Pagination: 1147-51 Citation Subset: IM |
Copyright Information:
|
Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Pediatrics, University of Pennsylvania School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. Dennery@email.chop.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Maternal fine particulate matter exposure, polymorphism in xenobiotic-metabolizing genes and offspri...
Next Document: Structural differentiation of bacterial communities in indole-degrading bioreactors under denitrifyi...