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Oxidative stress in cardiac and skeletal muscle dysfunction associated with diabetes mellitus.
MedLine Citation:
PMID:  21297915     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Diabetes mellitus increases the risk of heart failure independently of underlying coronary artery disease. It also causes skeletal muscle dysfunction, which is responsible for reduced exercise capacity commonly seen in heart failure. The underlying pathogenesis is partially understood. Several factors may contribute to the development of cardiac and skeletal muscle dysfunction in heart failure and diabetes mellitus. Based on the findings in animal models, this review discusses the role of oxidative stress that may be involved in the development and progression of cardiac and skeletal dysfunction associated with diabetes.
Authors:
Hiroyuki Tsutsui; Shintaro Kinugawa; Shouji Matsushima; Takashi Yokota
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Publication Detail:
Type:  Journal Article     Date:  2010-12-28
Journal Detail:
Title:  Journal of clinical biochemistry and nutrition     Volume:  48     ISSN:  1880-5086     ISO Abbreviation:  J Clin Biochem Nutr     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-02-07     Completed Date:  2011-07-14     Revised Date:  2011-07-25    
Medline Journal Info:
Nlm Unique ID:  8700907     Medline TA:  J Clin Biochem Nutr     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  68-71     Citation Subset:  -    
Affiliation:
Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, Sapporo 060-8638, Japan.
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