| [Oxidative stress and Alzheimer's disease]. | |
| | |
MedLine Citation:
|
PMID: 22348966 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Alzheimer's disease (AD) has become one of the most important and most interesting focuses in the field of medical and scientific research. Up to now, the pathogenesis of AD has not been completely clarified. However, the high-density of amyloid β-protein (Aβ) in senile plaques of AD brain and the neurotoxicity of Aβ have been indisputable facts. The mechanisms underlying Aβ neurotoxicity are very complicated, involving calcium overload, inflammation, ion channel dysfunction, oxidative stress and so on. Among all of those, the mechanism of oxidative stress in Aβ neurotoxicity and the experimental progress of antioxidants in AD treatment have been widely reported in recent years. This review mainly discussed current research progresses on the oxidative stress of Aβ, so as to provide readers with some clues to the antioxidant therapy of AD. |
| | |
Authors:
|
Xiao-Jie Liu; Wei Yang; Jin-Shun Qi |
Publication Detail:
|
Type: English Abstract; Journal Article |
Journal Detail:
|
Title: Sheng li xue bao : [Acta physiologica Sinica] Volume: 64 ISSN: 0371-0874 ISO Abbreviation: Sheng Li Xue Bao Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-02-21 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 20730130R Medline TA: Sheng Li Xue Bao Country: China |
Other Details:
|
Languages: chi Pagination: 87-95 Citation Subset: IM |
Affiliation:
|
Department of Physiology, Key Laboratory for Cellular Physiology of Ministry of Education, Shanxi Medical University, Taiyuan 030001, China. E-mail: jinshunqi@sohu.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: [Expression of Kir2.1, SCN5a and SCN1b channel genes in mouse cardiomyocytes with various electric p...
Next Document: [Effects of visfatin gene polymorphisms on glycolipid metabolism and exercise-induced weight reducti...