| Oxidative and antioxidant changes during formation of unstable atherosclerotic plaque. | |
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MedLine Citation:
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PMID: 18683489 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Oxidative and antioxidant parameters (content of LPO products and oxidized proteins, initial level of paraoxonase, content of alpha-tocopherol, retinol, and beta-carotene) were studied at different stages of atherosclerotic foci development in coronary arteries: intact intima, lipid spot, stable young plaque, unstable plaque, stable plaque with fibrosis/ calcinosis, and in various types of unstable plaques. The most typical sign of unstable plaques is high level of LPO products and low retinol content. |
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Authors:
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Yu I Ragino; A M Chernyavski; Ya V Polonskaya; A M Volkov; E V Semaeva; M I Voevoda |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Bulletin of experimental biology and medicine Volume: 144 ISSN: 0007-4888 ISO Abbreviation: Bull. Exp. Biol. Med. Publication Date: 2007 Nov |
Date Detail:
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Created Date: 2008-08-07 Completed Date: 2008-12-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372557 Medline TA: Bull Exp Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 661-3 Citation Subset: IM |
Affiliation:
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Institute of Therapy, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk. ragino@online.nsk.su |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Antioxidants / metabolism* Aryldialkylphosphatase / metabolism Atherosclerosis / metabolism*, pathology Coronary Vessels / metabolism, pathology Humans Male Malondialdehyde / metabolism Middle Aged Oxidants / metabolism* Oxidation-Reduction Spectrometry, Fluorescence Vitamin A / metabolism alpha-Tocopherol / metabolism beta Carotene / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Oxidants; 11103-57-4/Vitamin A; 542-78-9/Malondialdehyde; 59-02-9/alpha-Tocopherol; 7235-40-7/beta Carotene; EC 3.1.8.1/Aryldialkylphosphatase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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