Document Detail

Oxidation of ascorbic acid in stored orange juice is associated with reduced plasma vitamin C concentrations and elevated lipid peroxides.
MedLine Citation:
PMID:  15635354     Owner:  NLM     Status:  MEDLINE    
Ascorbic acid oxidizes in refrigerated orange juice, but the physiological relevance of this deterioration is unknown. We compared changes in plasma vitamin C and total lipid peroxides (thiobarbituric acid-reactive substances, TBARS) in the 2-hour period following consumption of commercial orange juices on day 1 vs day 8 of storage (4 degrees C). The ascorbic acid content decreased significantly after storage in juice reconstituted from frozen concentrate (117+/-8 vs 89+/-8 mg/8 fl oz, P =.001), but did not change in chilled juice (69+/-5 vs 64+/-12 mg/8 fl oz.). The mean incremental TBARS value was less on day 1 vs day 8 for juice from frozen concentrate (-0.46+/-0.72 and 0.70+/-0.53, P =.046), but did not differ for chilled juice (0.00+/-0.49 and 0.54+/-0.89). The incremental values for plasma TBARS and vitamin C in the 2-hour postprandial period were inversely related (r=-0.48, P =.017). These data indicate that the loss of ascorbic acid in refrigerated juice may impact postprandial oxidative stress.
Carol S Johnston; Joanna C Hale
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the American Dietetic Association     Volume:  105     ISSN:  0002-8223     ISO Abbreviation:  J Am Diet Assoc     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-06     Completed Date:  2005-02-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7503061     Medline TA:  J Am Diet Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  106-9     Citation Subset:  AIM; IM    
Department of Nutrition, Arizona State University, 7001 E Williams Field Rd, Mesa, AZ 85212, USA.
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MeSH Terms
Antioxidants / administration & dosage,  metabolism*
Ascorbic Acid / administration & dosage,  blood,  metabolism*
Beverages / analysis*
Citrus sinensis*
Cold Temperature
Cross-Over Studies
Drug Stability
Food Handling / methods
Food Preservation / methods*
Frozen Foods / standards
Lipid Peroxidation / drug effects,  physiology*
Postprandial Period
Thiobarbituric Acid Reactive Substances / analysis
Time Factors
Reg. No./Substance:
0/Antioxidants; 0/Thiobarbituric Acid Reactive Substances; 50-81-7/Ascorbic Acid

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