Document Detail


Oxidation of NAD dimers by horseradish peroxidase.
MedLine Citation:
PMID:  3994664     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Horseradish peroxidase catalyses the oxidation of NAD dimers, (NAD)2, to NAD+ in accordance with a reaction that is pH-dependent and requires 1 mol of O2 per 2 mol of (NAD)2. Horseradish peroxidase also catalyses the peroxidation of (NAD)2 to NAD+. In contrast, bacterial NADH peroxidase does not catalyse the peroxidation or the oxidation of (NAD)2. A free-radical mechanism is proposed for both horseradish-peroxidase-catalysed oxidation and peroxidation of (NAD)2.
Authors:
L Avigliano; V Carelli; A Casini; A Finazzi-Agrò; F Liberatore
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Biochemical journal     Volume:  226     ISSN:  0264-6021     ISO Abbreviation:  Biochem. J.     Publication Date:  1985 Mar 
Date Detail:
Created Date:  1985-05-24     Completed Date:  1985-05-24     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2984726R     Medline TA:  Biochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  391-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Chromatography, High Pressure Liquid
Horseradish Peroxidase / metabolism*
Hydrogen-Ion Concentration
Macromolecular Substances
Models, Chemical
NAD / metabolism*
Oxidation-Reduction
Peroxidases / metabolism*
Chemical
Reg. No./Substance:
0/Macromolecular Substances; 53-84-9/NAD; EC 1.11.1.-/Horseradish Peroxidase; EC 1.11.1.-/Peroxidases
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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