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Oxaliplatin-induced Pulmonary Fibrosis: Two Case Reports.
MedLine Citation:
PMID:  22102978     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Oxaliplatin with infusional 5-fluorouracil plus leucovorin (FOLFOX regimen) is the one of the standard chemotherapy regimens for treating a colorectal carcinoma. The most common side effects include neutropenia, diarrhea, vomiting and peripheral neuropathy, and these are moderate and manageable. However, pulmonary toxicity is rarely reported to be associated with the FOLFOX regimen. Moreover, there is no established guideline for the management of this side effect. Here, along with a literature review, we report two cases of rapidly developing pulmonary fibrosis related to the use of the FOLFOX regimen in patients with colorectal carcinomas.
Authors:
Chun-Geun Ryu; Eun-Joo Jung; Gangmi Kim; Su Ran Kim; Dae-Yong Hwang
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Publication Detail:
Type:  Journal Article     Date:  2011-10-31
Journal Detail:
Title:  Journal of the Korean Society of Coloproctology     Volume:  27     ISSN:  2093-7830     ISO Abbreviation:  J Korean Soc Coloproctol     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-11-21     Completed Date:  2011-11-23     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101546077     Medline TA:  J Korean Soc Coloproctol     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  266-9     Citation Subset:  -    
Affiliation:
Department of Surgery, Colorectal Cancer Center, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
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