Document Detail


Oxalate-crystals in different tissues following intoxication with ethylene glycol: three case reports.
MedLine Citation:
PMID:  19251453     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three alcoholics (62 years, 47 years, 83 years) died between 11 and 18 h after ingestion of ethylene glycol (EG). One person committed suicide. Observed symptoms of intoxication were seizures, respiratory depression, arrhythmias and hypotonia. All died in hospital after failed attempts at resuscitation, one person did so after an 11h dialysis treatment. EG was detected in blood in concentrations of between 1 and 3mg/L (toxic range: >0.3mg/L). One case presented a blood alcohol concentration (bac) of 1.14 per thousand. Further toxic substances were not found. Using special staining techniques, oxalate crystals were found in samples from the kidneys, explaining renal failure, and in the medial layer of cerebral vessels.
Authors:
Heike Wollersen; Freidoon Erdmann; Manfred Risse; Reinhard Dettmeyer
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-02-28
Journal Detail:
Title:  Legal medicine (Tokyo, Japan)     Volume:  11 Suppl 1     ISSN:  1873-4162     ISO Abbreviation:  Leg Med (Tokyo)     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-05-26     Completed Date:  2010-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100889186     Medline TA:  Leg Med (Tokyo)     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  S488-90     Citation Subset:  IM    
Affiliation:
Institute of Forensic Medicine, University of Giessen, Frankfurter Str. 58, 35392 Giessen, Germany. heike.wollersen@forens.med.uni-giessen.de
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MeSH Terms
Descriptor/Qualifier:
Aged, 80 and over
Alcoholism / complications
Calcium Oxalate / analysis*
Central Nervous System Depressants / blood
Cerebral Arteries / chemistry,  pathology
Cerebral Veins / chemistry,  pathology
Crystallization
Ethanol / blood
Ethylene Glycol / analysis,  poisoning*
Female
Forensic Pathology
Forensic Toxicology
Humans
Kidney / chemistry,  pathology
Kidney Failure, Acute / chemically induced
Liver / chemistry
Male
Middle Aged
Suicide
Chemical
Reg. No./Substance:
0/Central Nervous System Depressants; 107-21-1/Ethylene Glycol; 25454-23-3/Calcium Oxalate; 64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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