Document Detail

Ovulation induction and ovarian tumours: the debate continues.
MedLine Citation:
PMID:  10323063     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To critically review the published literature regarding the proposed association of ovarian stimulation and increased risk of ovarian tumors. DESIGN: A medline search (1966-1997) was done to identify case reports and epidemiological studies relevant to the issue in question. Review articles and critical reappraisals in the form of comments on studies done were also used. RESULTS: Various case reports, studies and review articles were identified as most relevant. CONCLUSION: Despite a few studies showing an apparent association between ovulation induction and ovarian cancer, support for their results has not been forthcoming. From the available data a causal relationship is not substantiated. To settle this issue large prospective studies are needed. Meanwhile, close clinical surveillance of patients being treated with ovulation induction is required.
A Murad
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  48     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-05-28     Completed Date:  1999-05-28     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  PAKISTAN    
Other Details:
Languages:  eng     Pagination:  353-6     Citation Subset:  IM    
Aga Khan University, Karachi.
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MeSH Terms
Ovarian Neoplasms / etiology*
Ovulation Induction / adverse effects*

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