| Ovulation induction in polycystic ovary syndrome: No. 242, May 2010. | |
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MedLine Citation:
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PMID: 20848729 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To review current non-pharmacologic and pharmacologic options for ovulation induction in women with polycystic ovary syndrome (PCOS). OPTIONS: This guideline reviews the evidence for the various options for ovulation induction in PCOS. OUTCOMES: Ovulation, pregnancy and live birth rates, risks, and side effects are the outcomes of interest. EVIDENCE: Published literature was retrieved through searches of Medline using appropriate controlled vocabulary and key words. Results were restricted to systematic reviews, randomized control trials/controlled clinical trials, and observational studies. Grey (unpublished) literature was identified through searching the websites of health technology assessment and of health technology assessment-related agencies, clinical practice guideline collections, clinical trial registries, and national and international medical specialty societies. VALUES: The evidence gathered was reviewed and evaluated by the Reproductive Endocrinology and Infertility Committee of the Society of Obstetricians and Gynaecologists of Canada. The quality of evidence was quantified using the Canadian Task Force on Preventive Health Care. BENEFITS, HARMS, AND COSTS: Benefits include weight reduction and improvements in ovulation, pregnancy, and live birth rates. Potential harms include medication side effects and multiple pregnancies. VALIDATION: These guidelines have been reviewed and approved by the Reproductive Endocrinology and Infertility Committee of the SOGC. |
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Authors:
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Tannys D R Vause; Anthony P Cheung; Sony Sierra; Paul Claman; James Graham; Jo-Anne Guillemin; Louise Lapensée; Sabrina Steward; Benjamin Chee-Man Wong; |
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Publication Detail:
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Type: Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Volume: 111 ISSN: 1879-3479 ISO Abbreviation: Int J Gynaecol Obstet Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-16 Completed Date: 2010-12-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0210174 Medline TA: Int J Gynaecol Obstet Country: Ireland |
Other Details:
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Languages: eng Pagination: 95-100 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aromatase Inhibitors
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therapeutic use* Clomiphene / therapeutic use* Female Fertility Agents, Female / therapeutic use* Fertilization in Vitro Gonadotropins / therapeutic use* Humans Hypoglycemic Agents / therapeutic use* Infertility, Female / drug therapy*, surgery Metformin / therapeutic use* Ovary / surgery Ovulation Induction / methods* Polycystic Ovary Syndrome / drug therapy* Pregnancy Randomized Controlled Trials as Topic Weight Loss |
| Chemical | |
Reg. No./Substance:
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0/Aromatase Inhibitors; 0/Fertility Agents, Female; 0/Gonadotropins; 0/Hypoglycemic Agents; 657-24-9/Metformin; 911-45-5/Clomiphene |
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