Document Detail

Ovulation induction in the ovulatory woman.
MedLine Citation:
PMID:  8988528     Owner:  NLM     Status:  MEDLINE    
Controlled ovarian hyperstimulation is frequently employed as empiric therapy for the treatment of unexplained infertility, mild male factor, cervical factor, and treated endometriosis. Prescribed in the form of either clomiphene citrate or gonadotropins, it is often combined with intrauterine insemination and offered to patients as a less expensive and less invasive alternative to the assisted reproductive technologies. Efficacy studies for these regimens are very important, as patients who would appear to be ideal candidates for this empiric therapy frequently do not suffer from absolute infertility; rather they are often subfertile, and may conceive spontaneously given enough time. Although there are few well-designed, controlled trials that assess the effectiveness of this form of therapy, the majority of the published data do suggest an improvement in pregnancy rates when compared to expectant management.
K M Silverberg
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in reproductive endocrinology     Volume:  14     ISSN:  0734-8630     ISO Abbreviation:  Semin. Reprod. Endocrinol.     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1997-03-26     Completed Date:  1997-03-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8308354     Medline TA:  Semin Reprod Endocrinol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  339-44     Citation Subset:  IM    
Division of Reproductive Endocrinology and Infertility, University of Texas Health Sciences Center, San Antonio, USA.
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MeSH Terms
Clomiphene / therapeutic use
Endometriosis / complications
Fertility Agents, Female / therapeutic use
Gonadotropin-Releasing Hormone / analogs & derivatives
Gonadotropins, Pituitary / therapeutic use
Infertility, Female / etiology,  physiopathology,  therapy*
Infertility, Male / complications
Insemination, Artificial / methods
Ovulation / physiology*
Ovulation Induction / methods*
Reg. No./Substance:
0/Fertility Agents, Female; 0/Gonadotropins, Pituitary; 33515-09-2/Gonadotropin-Releasing Hormone; 911-45-5/Clomiphene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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