Overweight, air and noise pollution: Universal risk factors for pediatric pre-hypertension. | |
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PMID: 22973395 Owner: NLM Status: PubMed-not-MEDLINE |
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Pediatric pre-hypertension (pre-HTN) has a complex multifactorial etiology. Although most cases are secondary to other disorders, a substantial number of children and adolescents have primary or essential HTN and pre-HTN. The gene-gene and gene-environment interactions should be considered in this context. The strong relationship of pre-HTN with environmental factors such as air pollution, noise pollution and passive smoking and obesity suggest that its prevalence will be escalating.Exposure to ambient particulate matters may increase blood pressure (BP) within hours to days. The underlying biologic pathways include autonomic nervous system imbalance and arterial vascular dysfunction or vasoconstriction because of systemic oxidative stress and inflammation. Likewise, tobacco smoke exposure of pregnant mothers increases systolic BP of their offspring in early infancy. Parental smoking also independently affects systolic BP among healthy preschool children. Noise exposure, notably in night, is associated with catecholamine secretion, increased BP and a pre-HTN state even in pre-school age children.Excess weight is associated with dysfunction of the adipose tissue, consisting of enlarged hypertrophied adipocytes, increased infiltration by macrophages and variations in secretion of adipokines and free fatty acids. These changes would result in chronic vascular inflammation, oxidative stress, activation of the renin-angiotensin-aldosterone system and sympathetic response, and ultimately to pre-HTN from childhood.Prevention and control of the modifiable risk factors of pre-HTN from prenatal period can have long-term health impact on primordial and primary prevention of chronic non-communicable diseases. This review presents a general view on the diagnosis, prevalence and etiology of pre-HTN along with practical measures for its prevention and control. |
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Roya Kelishadi; Parinaz Poursafa; Kasra Keramatian |
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Type: Journal Article |
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Title: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences Volume: 16 ISSN: 1735-7136 ISO Abbreviation: J Res Med Sci Publication Date: 2011 Sep |
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Created Date: 2012-09-13 Completed Date: 2012-10-02 Revised Date: 2013-05-30 |
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Nlm Unique ID: 101235599 Medline TA: J Res Med Sci Country: Iran |
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Languages: eng Pagination: 1234-50 Citation Subset: - |
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Professor, Department of Paediatrics, Child Health Promotion Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. |
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Journal Information Journal ID (nlm-ta): J Res Med Sci Journal ID (iso-abbrev): J Res Med Sci Journal ID (publisher-id): JRMS ISSN: 1735-1995 ISSN: 1735-7136 Publisher: Medknow Publications & Media Pvt Ltd, India |
Article Information Copyright: © Journal of Research in Medical Sciences open-access: Received Day: 28 Month: 8 Year: 2011 Accepted Day: 13 Month: 9 Year: 2011 Print publication date: Month: 9 Year: 2011 Volume: 16 Issue: 9 First Page: 1234 Last Page: 1250 ID: 3430051 PubMed Id: 22973395 Publisher Id: JRMS-16-1234 |
Overweight, air and noise pollution: Universal risk factors for pediatric pre-hypertension | |
Roya Kelishadi1 | |
Parinaz Poursafa2 | |
Kasra Keramatian3 | |
1-Professor, Department of Paediatrics, Child Health Promotion Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran |
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2-Environment Research Center, Isfahan University of Medical Sciences, Isfahan, Iran |
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3-Child Health Promotion Research Center, Isfahan University of Medical Sciences, Isfahan, Iran |
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Correspondence:
Corresponding Author: Parinaz Poursafa E-mail: parinaz.poursafa@gmail.com |
Hypertension (HTN) is the leading risk factor for cardiovascular disease with a worldwide prevalence of near one billion. It is well-established that HTN has a multifactorial etiology; it is a polygenic disease involving a major influence of various environmental factors.1–5
A growing body of evidence demonstrated that raised blood pressure (BP) during adulthood has its root in the childhood.6–8 In other words, high BP during childhood predicts long-term outcome in their future life. Some research on changing cardiovascular markers among hypertensive children as well as autopsy studies demonstrated aortic and heart vessels atherosclerotic changes that support this idea. In addition, it is documented that the higher systolic BP in children predicts the stiffer arteries during adulthood.7–11
The supporting data indicates that not only high BP significantly damages vital organs function in the future life of children and adolescent, but also pre-hypertension (pre-HTN) has the same harmful effects.9, 10, 12, 13 The Fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents highlighted that all children aged above 3 years who are seen in a medical setting should have their BP measured.14 It also illustrated the concept of pre-HTN after that the same term was developed for adults by the Joint National Committee on prevention detection evaluation and treatment of high blood pressure seventh report (JNC7). This term is used when a person's BP is elevated above normal but not to the level considered to be HTN.15
Given the increasing evidence on tracking of BP from childhood into adult life, the relative contributions of genetic, prenatal, environmental, biological and behavioral determinants to pediatric pre-HTN should be underscored. This review emphasizes on the importance and determinants of pre-HTN among children and adolescents, and highlights the modifiable factors that may be effective in primordial prevention of many chronic non-communicable diseases.
For this review, we identified studies published in the English language from 1990 to 2011, by a World Wide Web-based literature search using PubMed , Medline, Ovid MEDLINE(R) in process and other non-indexed citations, Allied and Complementary Medicine (AMED),Cumulative Index to Nursing and Allied Health Literature (CINAHL) ,Scopus, CAB Abstracts , and Global Health. The following search terms were used: blood pressure, hypertension, hypertensive, high blood pressure, pre-hypertension, lifestyle, environment, genetics, children, adolescents, and prevention. Data on study design and location, confounding factors, health outcomes, and study findings were extracted from the selected studies. We also used secondary references cited by the articles recognized in the primary search.
The diagnosis of pre-HTN needs multiple measurements, taken at least in three occasions over a period of time. Home and ambulatory BP measurements are more precise, but are recommended for special cases. In children and adolescents, home BP is lower than daytime ambulatory BP. This difference may be because of the daytime physical activity of this age group. Stage I hypertension is defined as a mean BP level from the 95th percentile to 5mmHg above the 99th percentile. Stage II hypertension is considered as an average BP exceeding 5mmHg above the 99th percentile.6, 14
The BP percentiles are constructed in some countries, and have reported slightly higher BP levels in children living in Northern Europe16, 17 and South Asia18 than those living in the US,6, 14 however a national study in Iran revealed reference curves consistent with the US curves.19
During growth, BP increases with age and body size; thus the accurate diagnosis of abnormal BP levels requires the use of standardized charts by age, gender and height.6, 14 Despite the report of Collins et al. which challenged the recent method of diagnosis of these disorders in the pediatric age groups,20 clinicians use the national high blood pressure education program working group guideline.6, 14, 21 In accordance with this guideline, pre-HTN is defined as the average systolic or diastolic blood pressure between 90th and 95th percentile in more than three different visits, and HTN as the average BP values more than 95th percentile. Quantities lower than 90th percentiles are considerate as the normal BP. The definition of pre-HTN is similar in adolescents of all ages, and is considered as BP > 120/80 mmHg.6, 14, 21, 22
The importance of pre-HTN in children and adolescents has different aspects. While increasing evidence is now available on the prevalence of pre-HTN and HTN in the pediatric age group and on escalating number of the cases of essential HTN in adolescence, there is also evidence of BP tracking, indicating that children and adolescents with pre-HTN tend to maintain that position over time.6, 22–25
Limited evidences exist on the prevalence of pre-HTN in children and adolescents. A summary of different results is presented in Table 1.9, 10, 12, 26–40 This prevalence has a wide range, and is usually about 4%, but it has been reported as high as 15.7% in adolescents.39 Serial BP measurement over time showed that 14% of adolescents with pre-HTN developed HTN in 2 years, which shows an incidence rate of about 7% per year for HTN. In the same study, after two years of follow up, 43% of girls and 68% of boys with high risk BP values developed pre-HTN.4
Pediatric HTN and pre-HTN have a complex multifactorial etiology. Although most cases are secondary to causes as renal, cardiovascular or endocrine disorders, a substantial number of children and adolescents are currently diagnosed with primary or essential HTN and pre-HTN.41 Some of the most important etiologies are as follows:
There is a growing body of evidence in detecting mutations and different combinations of genetic variations which may cause HTN and pre-HTN. Potentially variations were identified, which were associated with quantitative differences in the expression of multiple genes such as the differences in expression of the genes coding for the angiotensin-converting enzyme and for the natriuretic peptide receptor.22, 42–48 However the etiology is more complex and the gene-gene and gene-environment interactions should be considered in this context.49
Exposures to various environmental factors before and after birth have harmful effects on cardiovascular system.50 Various environmental risk factors are identified for pre-HTN, the most important ones being air pollution, noise pollution and second-hand smoking.
A growing body of evidence exists about the effect of air pollutants, notably particulate matter (PM) on pre-HTN. This association was found to be independent of aerologic factors like weather, temperature or humidity and of major cardiovascular risk factors such as age, diabetes, dyslipidemia and obesity.51–54
Accumulating evidences suggest that exposure to ambient levels of PM may increase BP within hours to days and can result in a prohypertensive response. The underlying biologic pathways include autonomic nervous system imbalance and arterial vascular dysfunction or vasoconstriction because of systemic oxidative stress and inflammation.22, 55, 56 Given the harmful effects of air pollutants, notably PM, on various organs and on underlying mechanisms of atherosclerosis and endothelial dysfunction from childhood,57–64 preventive measures should be considered from early life. The Multi-Ethnic Study of Atherosclerosis showed that traffic-related exposure may increase systolic BP, and in turn left ventricular mass index. The increase in this index has been consistent with 5.6 mmHg elevation in BP.65–67 Exposures to air pollutants other than PM, arsenic, lead, cadmium, solvents, and pesticides have also been linked to pre-HTN.68
The harmful effects of secondhand smoke on cardiovascular system are comparable to that of smoking.69 Some studies have documented the association of exposure to tobacco smoke with elevated BP in children and adolescents. Tobacco smoke exposure of pregnant mothers has a considerable effect on increasing systolic BP of their offspring in early infancy.70
A recent large population-based study showed that parental smoking independently affects systolic BP among healthy preschool children even after correction for other risk factors, such as body mass index, parental hypertension, or birth weight.71 Likewise, a family-centered prospective study revealed this association among children and adolescents.72 This widespread and modifiable risk factor should be considered in primordial and primary prevention of pre-HTN.
The cardiovascular effects of environmental noise, notably on high BP, are well documented and rank second in terms of disability-adjusted life year (DALYs) after annoyance.73–75 It is also documented that environmental noise exposure may be associated with elevated BP in young adults, especially in female individuals.76
Night time noise has an effect on our blood pressure more than day time noise. The HYENA (Hypertension and Exposure to Noise near Airports) study was a large study conducted among individuals who had lived at least 5 years near any of six major European airports. It found significant exposure-response relationships between night-time aircraft and average daily road traffic noise exposure and elevated BP. Monitoring BP showed that systolic BP increased by 6.2 mmHg and diastolic BP by 7.4 mmHg. The association of noise pollution with increased BP remained significant even after adjustment for major confounders as health, socioeconomic and lifestyle factors including diet and physical activity.77–78
Noise exposure is associated with increased catecholamine secretion. In children, in addition to impairing reading comprehension and long-term memory, chronic noise exposure may be associated with increased BP and a pre-HTN state.79–81 Such association is reported even in pre-school age children.82
Some changes in BP levels cannot be explained by well-known determinants as anthropometric measures and lifestyle factors. For instance, comparison of data from 4 waves of the Korean National Health and Nutrition Examination Survey between 1998 and 2008 among children and adolescents with 10 to 19 years of age revealed significant decrease in mean BP as well as in the prevalence of pre-HTN and HTN. These changes were not explained by secular trend of childhood obesity, cigarette smoking, physical activity, dietary habits, sociodemographic factors and psychological factors as perceived stress and sleep duration.83 Such findings may be confirmatory evidence of the underlying role of environmental factors on BP levels and pre-HTN state in children and adolescents.
The interaction of gene and environment on the development of many chronic diseases and their risk factors is well-established. The discrepancies of human genome and modern lifestyle can, at least in part, explain the ongoing epidemics of chronic non-communicable diseases.84–90
Likewise, such interaction may have a pivotal role in the development of pre-HTN. A growing body of evidence exists about the link between fetal programming and pre-HTN later in life.91 The fetal origins of adult disease is related to insults to epigenetic modifications of genes.92 Such epigenetic process of establishing future diseases may affect some genes responsible for fetal and placental growth.93
It is suggested that environmental changes during the prenatal and perinatal periods may be associated with altered gene expression by epigenetic mechanisms resulting in pre-HTN, HTN, and other chronic diseases.94
The association of environmental fetal programming is documented in young children; it is shown that in 6-year-old children born at full term, intrauterine growth retardation was linked to pre-HTN.95 Different mechanisms are considered in this regard, one of them is about the role of oxidative stress. A recent experimental study showed that the intrauterine environment modifies oxidative pathways of gene expression in fetal kidneys, and this may be a mechanism of pre-HTN.96 It is also suggested that fetal programming of pre-HTN may be mediated by the fundamental role of hyperinsulinism and hyperleptinemia.97
Various factors as maternal obesity,98 dietary habits in pregnancy,99 and gestational diabetes100 are considered to be the underlying mechanism of restricted fetal growth, and in turn of pre-HTN. Of special concern in this context is the association of environmental pollutants and other chemical toxins, which may result in intrauterine growth retardation and its sequels. Environmental pollutants may influence vital cellular functions during critical periods of fetal development, and may change the structure or function of vital organs. Developmental epigenetics may lead to “adaptive” phenotypes to respond the needs of the later-life environment. Exposure to environmental pollutants and toxic chemicals may interfere with these programmed adaptive changes, and eventually may result in considerable increase in various disorders as pre-HTN.101–104
Excess weight is associated with dysfunction of the adipose tissue, consisting of enlarged hypertrophied adipocytes, increased infiltration by macrophages and variations in secretion of adipokines and free fatty acids. These changes would results in chronic vascular inflammation, oxidative stress, activation of the renin-angiotensin-aldosterone system and sympathetic response, and ultimately to pre-HTN.105 The association of overweight with pre-HTN and HTN in the pediatric age group is well-documented.106–114
A birth cohort demonstrated that maternal pre-pregnancy weight and BMI, and weight at the end of pregnancy are found to be positively associated with both systolic and diastolic BP in adolescent subjects of both sexes; maternal height was positively associated with systolic BP only among males.115
The strong association of elevated BP with excess weight along with the childhood obesity epidemic has led to increase in the prevalence of the cases of pediatric HTN. Comparison of national data in the US revealed an increase in mean systolic and diastolic BP levels,116 and an overall increase in the prevalence of pre-HTN and HTN in children and adolescents.26, 117
Considering the rapidly escalating trend of childhood obesity, it can be estimated that the population prevalence of pre-HTN and HTN will be increasing from childhood to adulthood. This is of crucial importance for low- and middle-income countries facing increasing levels of childhood obesity118–122 as well as an emerging epidemic of non-communicable diseases.123–127
The pre-HTN state during childhood and adolescence is associated with various lifestyle factors. Although smoking may be associated with elevated BP, but such evidence is limited in the pediatric age group. Diet and physical activity are known a pivotal role in the development, prevention and control of pediatric pre-HTN. Their impact may begin from early life.6, 128
Various factors have been considered in this regard:
Diet is known to be associated with mean BP level, and pre-HTN; this association is documented from early life. Infant-feeding may have lifelong health impact. The protective role of breast feeding against chronic diseases and cardiometabolic risk factors, including elevated BP, is well-established.129–132 Accumulating evidence exists on the protective effect of breast feeding during infancy on BP and pre-HTN in later life.19, 133
Results of systematic reviews and meta-analyses confirmed the protective role of breast feeding against elevated BP in later life.133–135 Although, the correlations were not strong, but even such small reduction in BP associated with breastfeeding could confer important benefits at population level.
A birth cohort showed that after 7.3 years of follow up, children who were bottle-fed during infancy had significantly higher systolic BP than those who were breast-fed.136 However, some studies have shown small effects of breast feeding on children's BP, and have suggested that such effect may become more evident during adolescence.137–139
In addition to the beneficial effects of breast feeding for future BP of infants, it may have protective effects against elevated BP for mothers. A recent study in Finland found that16-20 years after pregnancy, women who had breast-fed for less than 6 months had higher total body fat and cardiometabolic risk factors than mothers who had breast-fed for longer than 6 months or for longer than 10 months. The protective long-term effects of duration of postpartum lactation on risk factors including systolic and diastolic BP were independent of pre-pregnancy weight and BMI, menopausal status, smoking status, level of education, participation in past and present leisure-time physical activity and current dietary energy intake.140
The type and the beginning time of complementary foods may have lifelong health impacts.
One of its aspects is the intake of sodium (salt), and related harmful effect on the developing kidneys and blood pressure. One of the recent evidences in this regard came from a large cohort of 8-month-old infants in the UK. It showed that 70% of infants consumed more than 400 mg sodium per day, which is the maximum UK recommendation for sodium intake in infants.141
Given the suggested effect of salt intake from infancy to adulthood on BP, body weight and energy balance,142 high sodium intake by complimentary foods may increase the cases of pre-HTN in the future.
The important role of taste preference should be taken into account. A recent study showed that healthy and low-sodium foods can be simply introduced in the diet of most infants.143 Usually the taste preferences in new food acceptance in early life may persist lifelong, and may have long-term health effects. Pediatricians have a pivotal role in introducing healthy complimentary foods to families;144 and less-educated mothers need to be learned about infant feeding practices.145
Different guidelines have suggested low sodium intake in childhood and adolescence for prevention of pre-HTN and HTN.146–148 However, the current salt intake is far in excess of nutritional requirements in children and adolescents of many populations.126, 149–153 This high intake is reported even in very young children with 3 years of age.154
Of special concern is that the high sodium content is not limited to unhealthy foods as snacks and processed foods, those foods as bread, cheese and cereals considered as healthy with recommendation of daily consumption, are of main hidden sources of salt intake among children and adolescents.155
Various types of studies have confirmed the effect of salt intake and pre-HTN in the pediatric age group. A large population-based study in the UK showed that the increase in salt intake by 1g in children is associated with 0.4 mmHg rise in systolic BP and 0.6 mmHg rise in pulse pressure.156
It is also documented that in addition to the direct association of salt intake on BP, excess dietary sodium intake would affect thirst and may increase consumption of sugary beverages by children and adolescents; and in turn, it would increase the likelihood of obesity and pre-HTN.157
A meta-analysis of controlled trials assessed the effect of reducing salt intake on BP in children and adolescents demonstrated that a modest reduction in salt intake resulted in immediate decline in BP level.158
However, the effects of low-sodium intake on pre-HTN are controversial, and may be not generalizable. A Cochrane review suggested that the effect of low versus high sodium intake on blood pressure was greater in Black and Asian patients than in Caucasians. Magnitude of the effect in Caucasians with normal blood pressure does not warrant a general recommendation to reduce sodium intake.159
On the other hand, some harmful effects of lowering salt intake are reported. In a recent study among healthy participants, low-salt diet was independently associated with an increase in insulin resistance.160
The dietary recommendations for prevention and control of pediatric pre-HTN are not limited to reducing the salt intake. Findings of the 8-year follow up of children initially 3 to 6 years of age in the prospective Framingham Children's Study showed children who consumed more fruits and vegetables or more dairy products during the preschool age had smaller yearly increase in systolic BP in subsequent years. At early adolescence, children with higher intakes of fruits and vegetables and dairy products had a lower mean systolic BP than those with either high intake of one of these food groups or those with low intake of them. This longitudinal study confirmed that a diet rich in fruits, vegetables, and dairy products may have beneficial effects on BP during childhood.161 This type of diet is consistent with the classic Dietary Approaches to Stop Hypertension (DASH) including a diet high in fresh fruits, vegetables, whole grains, and low-fat dairy products, recommended for adults.162
The beneficial effects of a DASH-type diet on cardiometabolic risk factors of children and adolescents were documented too. A large national study in the US showed that after 10 years of follow up, adolescent girls with diet more close to the DASH eating pattern had smaller gains in BMI.163 Trials with dietary interventions using the DASH-type diet showed favorable results in controlling pre-HTN state in diabetic164, 165 and non-diabetic adolescents.166 These findings highlight the need to underscore the intake of fruits, vegetables, fiber and dairy in the diets of children and adolescents.
Physical activity is known to positively moderate BP. There is a large body of evidence about the association of physical activity and lower cardiovascular risk factors, including pre-HTN and HTN.9, 32, 113, 167, 168 A study among young children showed that physical activity was independently associated with lower BP even in prepubertal children.169
A recent systematic review confirmed the association of physical activity with lower BP in children, and emphasized on the role of physical fitness on prevention and control of cardiovascular risk factors in children.170
Although it is well documented that sedentary behaviors are associated with pre-HTN, but a recent study among adolescents demonstrated various correlations between different types of sedentary activities and BP levels. It showed that after adjusting for confounders, while each hour per day spent in screen time, watching TV and playing video games was associated with a significant increase in diastolic BP, each hour per day spent reading was associated with a decrease in systolic and diastolic BP.171
Another national study in the US revealed that high TV use, but not high computer use, and lack of moderate-to-vigorous intensity physical activity was associated with cardiometabolic risk factors among children and adolescents.172 Office- and population-based interventions have demonstrated that pre-HTN may be reversible by increase in physical activity.173–176
Among different types of physical activities, aerobic exercises are found to be useful for controlling pre-HTN.177, 178 Likewise , this kind of exercise has been successful in reducing systolic and diastolic BP among children and adolescents with pre-HTN and HTN.179
In general, a combination of lifestyle change including healthy dietary pattern and exercise training may improve pre-HTN state and vascular function in children and adolescents.6, 180, 181
Childhood onset of adult non-communicable diseases has become a substantial health problem. The strong relationship of pre-HTN with environmental factors and obesity along with the increasing environmental pollution and the childhood obesity epidemic suggest that the population prevalence of pediatric pre-HTN will be escalating, and there is already evidence that this trend is proceeding. Physicians and health professionals who care for children and adolescents should incorporate screening of adult non-communicable diseases into their practice. Prevention and control of pediatric pre-HTN is of crucial importance in primary prevention of such chronic diseases. Prevention and control of its modifiable risk factors such as air and noise pollution, passive smoking, overweight and unhealthy lifestyle, along with primordial prevention by good pregnancy care for prevention of low birth weight, encouraging breast feeding, and using healthy complimentary foods during infancy can impact the overall health of children and adolescents, as well as the prevention of chronic non-communicable diseases. Better knowledge on the etiology of these disease states will help preventive and targeted therapies.
RK planned and conducted the review, wrote and finalized it, PP and KK assisted in planning, conducting and writing the review. All authors read and approved the final draft of the paper.
Notes
Conflict of Interests Authors have no conflict of interests.
1. | Olafiranye O,Zizi F,Brimah P,Jean-Louis G,Makaryus AN,McFarlane S,et al. Management of Hypertension among Patients with Coronary Heart DiseaseInt J HypertensYear: 2011201165390321785704 |
2. | Clara JG,De Macedo ME,Pego M. Prevalence of isolated systolic hypertension in the population over 55 years old. Results from a national studyRev Port CardiolYear: 200726111817427833 |
3. | Kearney PM,Whelton M,Reynolds K,Whelton PK,He J. Worldwide prevalence of hypertension: a systematic reviewJ HypertensYear: 200422111915106785 |
4. | Rosamond W,Flegal K,Friday G,Furie K,Go A,Greenlund K,et al. Heart disease and stroke statistics--2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics SubcommitteeCirculationYear: 20071155e6917117194875 |
5. | Mittal BV,Singh AK. Hypertension in the developing world: challenges and opportunitiesAm J Kidney DisYear: 2010553590819962803 |
6. | Balagopal PB,de Ferranti SD,Cook S,Daniels SR,Gidding SS,Hayman LL,et al. Nontraditional risk factors and biomarkers for cardiovascular disease: mechanistic, research, and clinical considerations for youth: a scientific statement from the American Heart AssociationCirculationYear: 20111232327496921555711 |
7. | Sun SS,Grave GD,Siervogel RM,Pickoff AA,Arslanian SS,Daniels SR. Systolic blood pressure in childhood predicts hypertension and metabolic syndrome later in lifePediatricsYear: 200711922374617272612 |
8. | Berenson GS,Srinivasan SR,Bao W,Newman WP III,Tracy RE,Wattigney WA. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults.The Bogalusa Heart StudyN Engl J MedYear: 199833823165069614255 |
9. | Stabouli S,Kotsis V,Rizos Z,Toumanidis S,Karagianni C,Constantopoulos A,et al. Left ventricular mass in normotensive, prehypertensive and hypertensive children and adolescentsPediatr NephrolYear: 200924815455119444486 |
10. | Genovesi S,Pieruzzi F,Giussani M,Tono V,Stella A,Porta A,et al. Analysis of heart period and arterial pressure variability in childhood hypertension: key role of baroreflex impairmentHypertensionYear: 200851512899418378858 |
11. | Li S,Chen W,Srinivasan SR,Berenson GS. Childhood blood pressure as a predictor of arterial stiffness in young adults: the bogalusa heart studyHypertensionYear: 2004433541614744922 |
12. | Lubrano R,Travasso E,Raggi C,Guido G,Masciangelo R,Elli M. Blood pressure load, proteinuria and renal function in pre-hypertensive childrenPediatr NephrolYear: 20092448233119096881 |
13. | Lucini D,Mela GS,Malliani A,Pagani M. Impairment in cardiac autonomic regulation preceding arterial hypertension in humans: insights from spectral analysis of beat-by-beat cardiovascular variabilityCirculationYear: 2002106212673912438292 |
14. | The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescentsPediatricsYear: 200411425557615286277 |
15. | Chobanian AV,Bakris GL,Black HR,Cushman WC,Green LA,Izzo JL Jr,et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood PressureHypertensionYear: 200342612065214656957 |
16. | Jackson LV,Thalange NK,Cole TJ. Blood pressure centiles for Great BritainArch Dis ChildYear: 200792429830316905566 |
17. | Munkhaugen J,Lydersen S,Wideroe TE,Hallan S. Blood pressure reference values in adolescents: methodological aspects and suggestions for Northern Europe tables based on the Nord-Trondelag Health Study IIJ HypertensYear: 200826101912818806614 |
18. | Sung RY,Choi KC,So HK,Nelson EA,Li AM,Kwok CW,et al. Oscillometrically measured blood pressure in Hong Kong Chinese children and associations with anthropometric parametersJ HypertensYear: 20082646788418327076 |
19. | Kelishadi R,Ardalan G,Gheiratmand R,Majdzadeh R,Delavari A,Heshmat R,et al. Blood pressure and its influencing factors in a national representative sample of Iranian children and adolescents: the CASPIAN StudyEur J Cardiovasc Prev RehabilYear: 20061369566317143128 |
20. | Collins RT,Alpert BS. Pre-hypertension and hypertension in pediatrics: don’t let the statistics hide the pathologyJ PediatrYear: 20091552165919619748 |
21. | Update on the 1987 Task Force Report on High Blood Pressure in Children and Adolescents: a working group report from the National High Blood Pressure Education Program. National High Blood Pressure Education Program Working Group on Hypertension Control in Children and AdolescentsPediatricsYear: 1996984 Pt 1649588885941 |
22. | Long AN,Dagogo-Jack S. Comorbidities of diabetes and hypertension: mechanisms and approach to target organ protectionJ Clin Hypertens (Greenwich )Year: 20111342445121466619 |
23. | Gidding SS. Measuring children's blood pressure mattersCirculationYear: 2008117253163418574056 |
24. | Bao W,Threefoot SA,Srinivasan SR,Berenson GS. Essential hypertension predicted by tracking of elevated blood pressure from childhood to adulthood: the Bogalusa Heart StudyAm J HypertensYear: 199587657657546488 |
25. | Fuentes RM,Notkola IL,Shemeikka S,Tuomilehto J,Nissinen A. Tracking of systolic blood pressure during childhood: a 15-year follow-up population-based family study in eastern FinlandJ HypertensYear: 200220219520211821703 |
26. | Din-Dzietham R,Liu Y,Bielo MV,Shamsa F. High blood pressure trends in children and adolescents in national surveys, 1963 to 2002CirculationYear: 20071161314889617846287 |
27. | Salman Z,Kirk GD,Deboer MD. High Rate of Obesity-Associated Hypertension among Primary Schoolchildren in SudanInt J HypertensYear: 2010201162949221234364 |
28. | Sharma A,Grover N,Kaushik S,Bhardwaj R,Sankhyan N. Prevalence of hypertension among schoolchildren in ShimlaIndian PediatrYear: 20104710873620308762 |
29. | Ostchega Y,Carroll M,Prineas RJ,McDowell MA,Louis T,Tilert T. Trends of elevated blood pressure among children and adolescents: data from the National Health and Nutrition Examination Survey1988-2006Am J HypertensYear: 2009221596719039307 |
30. | Hansen ML,Gunn PW,Kaelber DC. Underdiagnosis of hypertension in children and adolescentsJAMAYear: 20072988874917712071 |
31. | Salvadori M,Sontrop JM,Garg AX,Truong J,Suri RS,Mahmud FH,et al. Elevated blood pressure in relation to overweight and obesity among children in a rural Canadian communityPediatricsYear: 20081224e821e82718829779 |
32. | Diaz A,Tringler M,Molina JD,Diaz MC,Geronimi V,Aguera D,et al. [Blood pressure control and arterial hypertension in children and adolescents from a rural population in Argentina: preliminary data from Vela Proyect]Arch Argent PediatrYear: 20101081687020204242 |
33. | Aglony IM,Arnaiz GP,Acevedo BM,Barja YS,Marquez US,Guzman AB,et al. [Blood pressure and family history of hypertension in children from Santiago, Chile]Rev Med ChilYear: 20091371394519399320 |
34. | Juarez-Rojas JG,Cardoso-Saldana GC,Posadas-Sanchez R,Medina-Urrutia AX,Yamamoto-Kimura L,Posadas-Romero C. Blood pressure and associated cardiovascular risk factors in adolescents of Mexico CityArch Cardiol MexYear: 20087843849119205546 |
35. | Culhane-Pera KA,Moua M,DeFor TA,Desai J. Cardiovascular disease risks in Hmong refugees from Wat Tham Krabok, ThailandJ Immigr Minor HealthYear: 2009115372919101803 |
36. | Liang YJ,Xi B,Hu YH,Wang C,Liu JT,Yan YK,et al. Trends in blood pressure and hypertension among Chinese children and adolescents: China Health and Nutrition Surveys 1991-2004Blood PressYear: 2010201455321047169 |
37. | Chiolero A,Paccaud F,Bovet P. Pre-hypertension and hypertension among adolescents of SwitzerlandJ PediatrYear: 20071516e24e2518035125 |
38. | Di BP,Forziato C,Sanguigno E,Di FT,Saitta F,Iardino MR,et al. Prehypertension in outpatient obese childrenAm J HypertensYear: 2009221213091319745818 |
39. | McNiece KL,Poffenbarger TS,Turner JL,Franco KD,Sorof JM,Portman RJ. Prevalence of hypertension and pre-hypertension among adolescentsJ PediatrYear: 200715066404 (644).17517252 |
40. | Falkner B,Gidding SS,Portman R,Rosner B. Blood pressure variability and classification of prehypertension and hypertension in adolescencePediatricsYear: 200812222384218676538 |
41. | Sanjad SA. Etiology of hypertension in children and adolescentsJ Med LibanYear: 2010583142521462842 |
42. | Smithies O,Kim HS,Takahashi N,Edgell MH. Importance of quantitative genetic variations in the etiology of hypertensionKidney IntYear: 200058622658011115061 |
43. | Melo LG,Steinhelper ME,Pang SC,Tse Y,Ackermann U. ANP in regulation of arterial pressure and fluid-electrolyte balance: lessons from genetic mouse modelsPhysiol GenomicsYear: 200031455811015600 |
44. | Kardia SL. Context-dependent genetic effects in hypertensionCurr Hypertens RepYear: 20002132810981124 |
45. | Tan KT,Dempsey A,Liew CC. Cardiac genes and gene databases for cardiovascular disease geneticsCurr Hypertens RepYear: 19991151810981042 |
46. | Paul M. [The renin-angiotensin system as the basic principle for hypertension and coronary heart diseases--role of genetic factors]Z KardiolYear: 2000894264810867998 |
47. | Marcano AC,Onipinla AK,Caulfield MJ,Munroe PB. Recent advances in the identification of genes for human hypertensionExpert Rev Cardiovasc TherYear: 2005347334116076282 |
48. | Dorn GW. The genomic architecture of sporadic heart failureCirc ResYear: 20111081012708321566223 |
49. | Moore JH,Williams SM. New strategies for identifying gene-gene interactions in hypertensionAnn MedYear: 2002342889512108579 |
50. | Mone SM,Gillman MW,Miller TL,Herman EH,Lipshultz SE. Effects of environmental exposures on the cardiovascular system: prenatal period through adolescencePediatricsYear: 20041134 Suppl10586915060200 |
51. | Roman AO,Prieto CM,Mancilla FP,Astudillo OP,Dussaubat AA,Miguel WC,et al. [Association between air pollution and cardiovascular risk]Rev Med ChilYear: 2009137912172420011965 |
52. | Walker B Jr,Mouton CP. Environmental influences on cardiovascular healthJ Natl Med AssocYear: 200810019810218277816 |
53. | Brook RD. Is air pollution a cause of cardiovascular disease? Updated review and controversiesRev Environ HealthYear: 20072221153717894203 |
54. | Poursafa P KR. What health professionals should know about the health effects of air pollution and climate change on children and pregnant mothersIran J Nurse Midwifery ResYear: 201116318 |
55. | Brook RD,Rajagopalan S,Pope CA III,Brook JR,Bhatnagar A,Diez-Roux AV,et al. Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart AssociationCirculationYear: 20101212123317820458016 |
56. | Johnson D,Parker JD. Air pollution exposure and self-reported cardiovascular diseaseEnviron ResYear: 20091095582919394925 |
57. | Kelishadi R,Mirghaffari N,Poursafa P,Gidding SS. Lifestyle and environmental factors associated with inflammation, oxidative stress and insulin resistance in childrenAtherosclerosisYear: 20092031311918692848 |
58. | Poursafa P,Kelishadi R,Lahijanzadeh A,Modaresi M,Javanmard SH,Assari R,et al. The relationship of air pollution and surrogate markers of endothelial dysfunction in a population-based sample of childrenBMC Public HealthYear: 20111111521332998 |
59. | Poursafa P,Kelishadi R,Moattar F,Rafiee L,Amin MM,Lahijanzadeh A,et al. Genetic variation in the association of air pollutants with a biomarker of vascular injury in children and adolescents in Isfahan, IranJ Res Med SciYear: 20111667334022091301 |
60. | KelishadiR PP. Air pollution and non-respiratory health hazards for childrenArch Med SciYear: 2010644839522371790 |
61. | Poursafa P,Kelishadi R,Amini A,Amini A,Amin MM,Lahijanzadeh M,et al. Association of air pollution and hematologic parameters in children and adolescentsJ Pediatr (Rio J)Year: 2011874350621842113 |
62. | Kargarfard M,Poursafa P,Rezanejad S,Mousavinasab F. Effects of exercise in polluted air on the aerobic power, serum lactate level and cell blood count of active individualsInt J Prev MedYear: 2011231455021811656 |
63. | Mansourian M,Javanmard SH,Poursafa P,Kelishadi R. Air pollution and hospitalization for respiratory diseases among children in isfahan, iranGhana Med JYear: 20104441384321416047 |
64. | Poursafa P,Kelishadi R. Air pollution, platelet activation and atherosclerosisInflamm Allergy Drug TargetsYear: 2010953879221091428 |
65. | Van Hee VC,Adar SD,Szpiro AA,Barr RG,Roux AD,Bluemke DA,et al. Common genetic variation, residential proximity to traffic exposure, and left ventricular mass: the multi-ethnic study of atherosclerosisEnviron Health PerspectYear: 20101187962920308035 |
66. | Van Hee VC,Adar SD,Szpiro AA,Barr RG,Bluemke DA,Diez Roux AV,et al. Exposure to traffic and left ventricular mass and function: the Multi-Ethnic Study of AtherosclerosisAm J Respir Crit Care MedYear: 200917998273419164703 |
67. | Auchincloss AH,Diez Roux AV,Dvonch JT,Brown PL,Barr RG,Daviglus ML,et al. Associations between recent exposure to ambient fine particulate matter and blood pressure in the Multi-ethnic Study of Atherosclerosis (MESA)Environ Health PerspectYear: 200811644869118414631 |
68. | Bhatnagar A. Environmental cardiology: studying mechanistic links between pollution and heart diseaseCirc ResYear: 200699769270517008598 |
69. | Barnoya J,Glantz SA. Cardiovascular effects of secondhand smoke: nearly as large as smokingCirculationYear: 20051112026849815911719 |
70. | Geerts CC,Grobbee DE,van der Ent CK,de Jong BM,van der Zalm MM,van Putte-Katier N,et al. Tobacco smoke exposure of pregnant mothers and blood pressure in their newborns: results from the wheezing illnesses study Leidsche Rijn birth cohortHypertensionYear: 2007503572817664395 |
71. | Simonetti GD,Schwertz R,Klett M,Hoffmann GF,Schaefer F,Wuhl E. Determinants of blood pressure in preschool children: the role of parental smokingCirculationYear: 20111233292821220729 |
72. | Schwandt P,Haas GM,Liepold E. Lifestyle and cardiovascular risk factors in 2001 child-parent pairs: the PEP Family Heart StudyAtherosclerosisYear: 20102132642820980001 |
73. | Lercher P,Botteldooren D,Widmann U,Uhrner U,Kammeringer E. Cardiovascular effects of environmental noise: research in AustriaNoise HealthYear: 201113522345021537108 |
74. | Lercher P,Botteldooren D,Widmann U,Uhrner U,Kammeringer E. Cardiovascular effects of environmental noise: research in AustriaNoise HealthYear: 201113522345021537108 |
75. | Vangelova KK,Deyanov CE. Blood pressure and serum lipids in industrial workers under intense noise and a hot environmentRev Environ HealthYear: 20072243031118351229 |
76. | Belojevic G,Paunovic K,Jakovljevic B,Stojanov V,Ilic J,Slepcevic V,et al. Cardiovascular effects of environmental noise: research in SerbiaNoise HealthYear: 201113522172021537105 |
77. | Chang TY,Lai YA,Hsieh HH,Lai JS,Liu CS. Effects of environmental noise exposure on ambulatory blood pressure in young adultsEnviron ResYear: 20091097900519559411 |
78. | Jarup L,Babisch W,Houthuijs D,Pershagen G,Katsouyanni K,Cadum E,et al. Hypertension and exposure to noise near airports: the HYENA studyEnviron Health PerspectYear: 200811633293318335099 |
79. | Jarup L,Dudley ML,Babisch W,Houthuijs D,Swart W,Pershagen G,et al. Hypertension and Exposure to Noise near Airports (HYENA): study design and noise exposure assessmentEnviron Health PerspectYear: 2005113111473816263498 |
80. | Stansfeld SA,Matheson MP. Noise pollution: non-auditory effects on healthBr Med BullYear: 2003682435714757721 |
81. | Cohen S,Evans GW,Krantz DS,Stokols D. Physiological, motivational, and cognitive effects of aircraft noise on children: moving from the laboratory to the fieldAm PsycholYear: 1980353231437377650 |
82. | Cohen S,Krantz DS,Evans GW,Stokols D,Kelly S. Aircraft noise and children: Longitudinal and cross-sectional evidence on adaptation to noise and the effectiveness of noise abatementJ Pers Soc PsycholYear: 198140233145 |
83. | Regecova V,Kellerova E. Effects of urban noise pollution on blood pressure and heart rate in preschool childrenJ HypertensYear: 1995134405127629400 |
84. | Khang YH,Lynch JW. Exploring determinants of secular decreases in childhood blood pressure and hypertensionCirculationYear: 2011124439740521730305 |
85. | Redon J,Cifkova R,Laurent S,Nilsson P,Narkiewicz K,Erdine S,et al. The metabolic syndrome in hypertension: European society of hypertension position statementJ HypertensYear: 20082610189190018806611 |
86. | Eaton SB,Eaton SB. An evolutionary perspective on human physical activity: implications for healthComp Biochem Physiol A Mol Integr PhysiolYear: 20031361153914527637 |
87. | Rosenberg A. The IUGR newbornSemin PerinatolYear: 20083232192418482625 |
88. | Guan J,Mao C,Feng X,Zhang H,Xu F,Geng C,et al. Fetal development of regulatory mechanisms for body fluid homeostasisBraz J Med Biol ResYear: 20084164465418560669 |
89. | Nomura Y,Brooks-Gunn J,Davey C,Ham J,Fifer WP. The role of perinatal problems in risk of co-morbid psychiatric and medical disorders in adulthoodPsychol MedYear: 200737913233417472762 |
90. | Picone O,Servely JL,Chavatte-Palmer P. [Developmental origin of human adult disease: which importance for obstetrical practice?]J Gynecol Obstet Biol Reprod (Paris)Year: 20073643384317321694 |
91. | Haimov-Kochman R. [Fetal programming--the intrauterine origin of adult morbidity]HarefuahYear: 2005144297101 (151, 150).16128013 |
92. | Redon J,Cifkova R,Laurent S,Nilsson P,Narkiewicz K,Erdine S,et al. Mechanisms of hypertension in the cardiometabolic syndromeJ HypertensYear: 20092734415119262221 |
93. | Xu XF,Du LZ. Epigenetics in neonatal diseasesChin Med J (Engl)Year: 20101232029485421034612 |
94. | Reik W,Dean W,Walter J. Epigenetic reprogramming in mammalian developmentScienceYear: 2001293553210899311498579 |
95. | Waterland RA,Jirtle RL. Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseasesNutritionYear: 200420163814698016 |
96. | Shankaran S,Das A,Bauer CR,Bada H,Lester B,Wright L,et al. Fetal origin of childhood disease: intrauterine growth restriction in term infants and risk for hypertension at 6 years of ageArch Pediatr Adolesc MedYear: 200616099778116953023 |
97. | Ghulmiyyah LM,Costantine MM,Yin H,Tamayo E,Clark SM,Hankins GD,et al. The role of oxidative stress in the developmental origin of adult hypertensionAm J Obstet GynecolYear: 2011 |
98. | Vickers MH,Breier BH,Cutfield WS,Hofman PL,Gluckman PD. Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hypercaloric nutritionAm J Physiol Endocrinol MetabYear: 20002791E83E8710893326 |
99. | Ornoy A. Prenatal origin of obesity and their complications: Gestational diabetes, maternal overweight and the paradoxical effects of fetal growth restriction and macrosomiaReprod ToxicolYear: 20113222051221620955 |
100. | Symonds ME. SSHMBH. Nutritional programming of the metabolic syndromeNat Rev EndocrinolYear: 20095116041119786987 |
101. | Nehiri T,Duong Van Huyen JP,Viltard M,Fassot C,Heudes D,Freund N,et al. Exposure to maternal diabetes induces salt-sensitive hypertension and impairs renal function in adult rat offspringDiabetesYear: 200857821677518443204 |
102. | Bezek S,Ujhazy E,Mach M,Navarova J,Dubovicky M. Developmental origin of chronic diseases: toxicological implicationInterdiscip ToxicolYear: 200811293121218103 |
103. | Wen X,Triche EW,Hogan JW,Shenassa ED,Buka SL. Prenatal factors for childhood blood pressure mediated by intrauterine and/or childhood growth?PediatricsYear: 20111273e713e72121300676 |
104. | Dotsch J,Plank C,Amann K. Fetal programming of renal functionPediatr NephrolYear: 2011 |
105. | Dores H,Santos P,Salvador F,Maia J,Paixao L,Pereira R,et al. Blood pressure in young adultsRev Port CardiolYear: 20102910149550821265492 |
106. | Dorresteijn JA,Visseren FL,Spiering W. Mechanisms linking obesity to hypertensionObes RevYear: 2011 |
107. | Flynn JT,Falkner BE. Obesity hypertension in adolescents: epidemiology, evaluation, and managementJ Clin Hypertens (Greenwich )Year: 20111353233121545393 |
108. | de Almeida FA,Konigsfeld HP,Machado LM,Canadas AF,Issa EY,Giordano RH,et al. Assessment of social and economic influences on blood pressure of adolescents in public and private schools: an epidemiological studyJ Bras NefrolYear: 2011332142921789427 |
109. | Knight JA. Diseases and disorders associated with excess body weightAnn Clin Lab SciYear: 20114121072121844568 |
110. | Sangun O,Dundar B,Kosker M,Pirgon O,Dundar N. Prevalence of Metabolic Syndrome in Obese Children and Adolescents using Three Different Criteria and Evaluation of Risk FactorsJ Clin Res Pediatr EndocrinolYear: 20113270621750635 |
111. | Saab PG,Fitzpatrick S,Lai B,McCalla JR. Elevated body mass index and obesity among ethnically diverse adolescentsEthn DisYear: 20112121768221749021 |
112. | Zhang YX,Wang SR. The relationship of body mass index distribution to relatively high blood pressure among children and adolescents in Shandong, ChinaAnn Hum BiolYear: 2011385630421745152 |
113. | Zhang YX,Wang SR. Monitoring of blood pressure in overweight and obese children in Shandong, ChinaAnn Hum BiolYear: 2011385603721609248 |
114. | Leung LC,Sung RY,So HK,Wong SN,Lee KW,Lee KP,et al. Prevalence and risk factors for hypertension in Hong Kong Chinese adolescents: waist circumference predicts hypertension, exercise decreases riskArch Dis ChildYear: 2011969804921586437 |
115. | Yeste D,Carrascosa A. [Obesity-related metabolic disorders in childhood and adolescence]An Pediatr (Barc )Year: 2011752135921571600 |
116. | Laura HC,Menezes AB,Noal RB,Hallal PC,Araujo CL. Maternal anthropometric characteristics in pregnancy and blood pressure among adolescents: 1993 live birth cohort, Pelotas, southern BrazilBMC Public HealthYear: 20101043420653949 |
117. | Wang Y,Zhang Q. Are American children and adolescents of low socioeconomic status at increased risk of obesity? Changes in the association between overweight and family income between 1971 and 2002Am J ClinNutrYear: 200684470716 |
118. | Martorell R,Kettel KL,Hughes ML,Grummer-Strawn LM. Overweight and obesity in preschool children from developing countriesInt J Obes Relat Metab DisordYear: 20002489596710951533 |
119. | Low LC. Childhood obesity in developing countriesWorld J PediatrYear: 201063197920706817 |
120. | Kelishadi R. Childhood overweight, obesity, and the metabolic syndrome in developing countriesEpidemiol RevYear: 200729627617478440 |
121. | Gupta DK,Shah P,Misra A,Bharadwaj S,Gulati S,Gupta N,et al. Secular trends in prevalence of overweight and obesity from 2006 to 2009 in urban asian Indian adolescents aged 14-17 yearsPLoS OneYear: 201162e1722121383840 |
122. | de OM,Blossner M,Borghi E. Global prevalence and trends of overweight and obesity among preschool childrenAm J Clin NutrYear: 201092512576420861173 |
123. | Dans A,Ng N,Varghese C,Tai ES,Firestone R,Bonita R. The rise of chronic non-communicable diseases in southeast Asia: time for actionLancetYear: 20113779766680921269677 |
124. | Bovet P,Viswanathan B,Shamlaye C,Romain S,Gedeon J. Addressing non-communicable diseases in the Seychelles: towards a comprehensive plan of actionGlob Health PromotYear: 2010172 Suppl374020595339 |
125. | Dalal S,Beunza JJ,Volmink J,Adebamowo C,Bajunirwe F,Njelekela M,et al. Non-communicable diseases in sub-Saharan Africa: what we know nowInt J EpidemiolYear: 201140488590121527446 |
126. | Misra A,Singhal N,Sivakumar B,Bhagat N,Jaiswal A,Khurana L. Nutrition Transition in India: Secular Trends in Dietary Intake and their Relationship to Diet-related Non-communicable DiseasesJ DiabetesYear: 2011 |
127. | Al-Daghri NM,Al-Attas OS,Alokail MS,Alkharfy KM,Yousef M,Sabico SL,et al. Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (riyadh cohort 2): a decade of an epidemicBMC MedYear: 201197621689399 |
128. | Katona E,Zrinyi M,Komonyi E,Lengyel S,Paragh G,Zatik J,et al. Factors influencing adolescent blood pressure: the Debrecen Hypertension StudyKidney Blood Press ResYear: 20113431889521502767 |
129. | de Armas MG,Megias SM,Modino SC,Bolanos PI,Guardiola PD,Alvarez TM. [Importance of breastfeeding in the prevalence of metabolic syndrome and degree of childhood obesity]Endocrinol NutrYear: 2009568400319959149 |
130. | Plagemann A,Harder T. Breast feeding and the risk of obesity and related metabolic diseases in the childMetab Syndr Relat DisordYear: 2005332223218370791 |
131. | Turck D. Later effects of breastfeeding practice: the evidenceNestle Nutr Workshop Ser Pediatr ProgramYear: 200760319 |
132. | Schack-Nielsen L,Michaelsen KF. Advances in our understanding of the biology of human milk and its effects on the offspringJ NutrYear: 20071372503S10S17237337 |
133. | Smithers L,McIntyre E. The impact of breastfeeding--translating recent evidence for practiceAust Fam PhysicianYear: 201039107576020890478 |
134. | Martin RM,Gunnell D,Smith GD. Breastfeeding in infancy and blood pressure in later life: systematic review and meta-analysisAm J EpidemiolYear: 20051611152615615909 |
135. | Owen CG,Whincup PH,Gilg JA,Cook DG. Effect of breast feeding in infancy on blood pressure in later life: systematic review and meta-analysisBMJYear: 2003327742511899514630752 |
136. | Wilson AC,Forsyth JS,Greene SA,Irvine L,Hau C,Howie PW. Relation of infant diet to childhood health: seven year follow up of cohort of children in Dundee infant feeding studyBMJYear: 199831671242159451261 |
137. | de Jonge LL,van Osch-Gevers L,Geelhoed JJ,Hofman A,Steegers EA,Helbing WA,et al. Breastfeeding is not associated with left cardiac structures and blood pressure during the first two years of life. The Generation R StudyEarly Hum DevYear: 2010868463820609534 |
138. | Fall CH,Borja JB,Osmond C,Richter L,Bhargava SK,Martorell R,et al. Infant-feeding patterns and cardiovascular risk factors in young adulthood: data from five cohorts in low- and middle-income countriesInt J EpidemiolYear: 2011401476220852257 |
139. | Fewtrell MS. Breast-feeding and later risk of CVD and obesity: evidence from randomised trialsProc Nutr SocYear: 201116 |
140. | Wiklund P,Xu L,Lyytikainen A,Saltevo J,Wang Q,Volgyi E,et al. Prolonged breast-feeding protects mothers from later-life obesity and related cardio-metabolic disordersPublic Health NutrYear: 20111821859508 |
141. | Cribb VL,Warren JM,Emmett PM. Contribution of inappropriate complementary foods to the salt intake of 8-month-old infantsEur J Clin NutrYear: 2011 |
142. | Coelho MS,Passadore MD,Gasparetti AL,Bibancos T,Prada PO,Furukawa LL,et al. High- or low-salt diet from weaning to adulthood: effect on body weight, food intake and energy balance in ratsNutr Metab Cardiovasc DisYear: 20061621485516487915 |
143. | Schwartz C,Chabanet C,Lange C,Issanchou S,Nicklaus S. The role of taste in food acceptance at the beginning of complementary feedingPhysiol BehavYear: 201110446465221554893 |
144. | Savino F,Zannino L,Laccisaglia A,Maccario S,Cresi F,Silvestro L,et al. Infant nutritional recommendations from pediatricians.Epidemiologic survey of feeding recommendations for the first year of life in PiedmontMinerva PediatrYear: 2004561738215249916 |
145. | Fein SB,Labiner-Wolfe J,Scanlon KS,Grummer-Strawn LM. Selected complementary feeding practices and their association with maternal educationPediatricsYear: 2008122Suppl 2S91S9718829837 |
146. | Kavey RE,Allada V,Daniels SR,Hayman LL,McCrindle BW,Newburger JW,et al. Cardiovascular risk reduction in high-risk pediatric patients: a scientific statement from the American Heart Association Expert Panel on Population and Prevention Science; the Councils on Cardiovascular Disease in the Young, Epidemiology and Prevention, Nutrition, Physical Activity and Metabolism, High Blood Pressure Research, Cardiovascular Nursing, and the Kidney in Heart Disease; and the Interdisciplinary Working Group on Quality of Care and Outcomes ResearchJ Cardiovasc NursYear: 20072232185317545824 |
147. | Kones R. Is prevention a fantasy, or the future of medicine? A panoramic view of recent data, status, and direction in cardiovascular preventionTher Adv Cardiovasc DisYear: 201151618121183531 |
148. | Gidding SS,Lichtenstein AH,Faith MS,Karpyn A,Mennella JA,Popkin B,et al. Implementing American Heart Association pediatric and adult nutrition guidelines: a scientific statement from the American Heart Association Nutrition Committee of the Council on Nutrition, Physical Activity and Metabolism, Council on Cardiovascular Disease in the Young, Council on Arteriosclerosis, Thrombosis and Vascular Biology, Council on Cardiovascular Nursing, Council on Epidemiology and Prevention, and Council for High Blood Pressure ResearchCirculationYear: 2009119811617519255356 |
149. | Hilbig A,Kersting M. 24h-Sodium excretion andhydration status in children and adolescents - Results of the DONALD StudyClinNutrYear: 2011 [Epub ahead of print]. |
150. | Eloranta AM,Lindi V,Schwab U,Kiiskinen S,Kalinkin M,Lakka HM,et al. Dietary factors and their associations with socioeconomic background in Finnish girls and boys 6-8 years of age: the PANIC StudyEur J Clin NutrYear: 2011 |
151. | Kawano Y. Salt intake in childrenHypertens ResYear: 2011347797821593739 |
152. | Girardet JP,Rieu D,Bocquet A,Bresson JL,Chouraqui JP,Darmaun D,et al. [Childhood diet and cardiovascular risk factors]Arch PediatrYear: 201017151919944575 |
153. | Costa FP,Machado SH. [Does the consumption of salt and food rich in sodium influence blood pressure in infants?]Cien Saude ColetYear: 201015Suppl 11383920640298 |
154. | Morinaga Y,Tsuchihashi T,Ohta Y,Matsumura K. Salt intake in 3-year-old Japanese childrenHypertens ResYear: 2011347836921593740 |
155. | Magriplis E,Farajian P,Pounis GD,Risvas G,Panagiotakos DB,Zampelas A. High sodium intake of children through ‘hidden’ food sources and its association with the Mediterranean diet: the GRECO studyJ HypertensYear: 201129610697621451420 |
156. | He FJ,Marrero NM,Macgregor GA. Salt and blood pressure in children and adolescentsJ Hum HypertensYear: 200822141117823599 |
157. | He FJ,Marrero NM,Macgregor GA. Salt intake is related to soft drink consumption in children and adolescents: a link to obesity?HypertensionYear: 20085136293418287345 |
158. | He FJ,Macgregor GA. Importance of salt in determining blood pressure in children: meta-analysis of controlled trialsHypertensionYear: 2006485861917000923 |
159. | Jurgens G,Graudal NA. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglycerideCochrane Database Syst RevYear: 20041CD00402214974053 |
160. | Garg R,Williams GH,Hurwitz S,Brown NJ,Hopkins PN,Adler GK. Low-salt diet increases insulin resistance in healthy subjectsMetabolismYear: 2011607965821036373 |
161. | Moore LL,Singer MR,Bradlee ML,Djousse L,Proctor MH,Cupples LA,et al. Intake of fruits, vegetables, and dairy products in early childhood and subsequent blood pressure changeEpidemiologyYear: 200516141115613939 |
162. | Sacks FM,Svetkey LP,Vollmer WM,Appel LJ,Bray GA,Harsha D,et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet.DASH-Sodium Collaborative Research GroupN Engl J MedYear: 2001344131011136953 |
163. | Berz JP,Singer MR,Guo X,Daniels SR,Moore LL. Use of a DASH food group score to predict excess weight gain in adolescent girls in the National Growth and Health StudyArch Pediatr Adolesc MedYear: 20111656540621646587 |
164. | Liese AD,Bortsov A,Gunther AL,Dabelea D,Reynolds K,Standiford DA,et al. Association of DASH diet with cardiovascular risk factors in youth with diabetes mellitus: the SEARCH for Diabetes in Youth studyCirculationYear: 2011123131410721422385 |
165. | Gunther AL,Liese AD,Bell RA,Dabelea D,Lawrence JM,Rodriguez BL,et al. Association between the dietary approaches to hypertension diet and hypertension in youth with diabetes mellitusHypertensionYear: 200953161219029488 |
166. | Couch SC,Saelens BE,Levin L,Dart K,Falciglia G,Daniels SR. The efficacy of a clinic-based behavioral nutrition intervention emphasizing a DASH-type diet for adolescents with elevated blood pressureJ PediatrYear: 2008152449450118346503 |
167. | Kelishadi R,Razaghi EM,Gouya MM,Ardalan G,Gheiratmand R,Delavari A,et al. Association of physical activity and the metabolic syndrome in children and adolescents: CASPIAN StudyHorm ResYear: 2007671465217035710 |
168. | Kelishadi R,Cook SR,Amra B,Adibi A. Factors associated with insulin resistance and non-alcoholic fatty liver disease among youthsAtherosclerosisYear: 200920425384319013572 |
169. | Gopinath B,Hardy LL,Teber E,Mitchell P. Association between physical activity and blood pressure in prepubertal childrenHypertens ResYear: 2011347851521525949 |
170. | Andersen LB,Riddoch C,Kriemler S,Hills A. Physical activity and cardiovascular risk factors in childrenBr J Sports MedYear: 20114511871621791456 |
171. | Gopinath B,Baur LA,Hardy LL,Kifley A,Rose KA,Wong TY,et al. Relationship between a range of sedentary behaviors and blood pressure during early adolescenceJ Hum HypertensYear: 2011 |
172. | Carson V,Janssen I. Volume, patterns, and types of sedentary behavior and cardio-metabolic health in children and adolescents: a cross-sectional studyBMC Public HealthYear: 20111127421542910 |
173. | Yoshinaga M,Hatake S,Tachikawa T,Shinomiya M,Miyazaki A,Takahashi H. Impact of Lifestyles of Adolescents and Their Parents on Cardiovascular Risk Factors in AdolescentsJ Atheroscler ThrombYear: 2011 |
174. | Kelishadi R,Hashemipour M,Sarrafzadegan N,Mohammadifard N,Alikhasy H,Beizaei M,et al. Effects of a lifestyle modification trial among phenotypically obese metabolically normal and phenotypically obese metabolically abnormal adolescents in comparison with phenotypically normal metabolically obese adolescentsMatern Child NutrYear: 2010632758620929499 |
175. | Sweat V,Bruzzese JM,Albert S,Pinero DJ,Fierman A,Convit A. The Banishing Obesity and Diabetes in Youth (BODY) Project: Description and Feasibility of a Program to Halt Obesity-Associated Disease Among Urban High School StudentsJ Community HealthYear: 2011 |
176. | Rush E,Reed P,McLennan S,Coppinger T,Simmons D,Graham D. A school-based obesity control programme: Project Energize. Two-year outcomesBr J NutrYear: 201117 |
177. | Aizawa K,Shoemaker JK,Overend TJ,Petrella RJ. Effects of lifestyle modification on central artery stiffness in metabolic syndrome subjects with pre-hypertension and/or pre-diabetesDiabetes Res Clin PractYear: 20098322495619097666 |
178. | Collier SR,Frechette V,Sandberg K,Schafer P,Ji H,Smulyan H,et al. Sex differences in resting hemodynamics and arterial stiffness following 4 weeks of resistance versus aerobic exercise training in individuals with pre-hypertension to stage 1 hypertensionBiol Sex DifferYear: 201121921867499 |
179. | Alpert BS. Exercise as a therapy to control hypertension in childrenInt J Sports MedYear: 200021Suppl 2S94S9611142600 |
180. | Kelishadi R,Hashemi M,Mohammadifard N,Asgary S,Khavarian N. Association of changes in oxidative and proinflammatory states with changes in vascular function after a lifestyle modification trial among obese childrenClin ChemYear: 20085411475317998270 |
181. | Ribeiro MM,Silva AG,Santos NS,Guazzelle I,Matos LN,Trombetta IC,et al. Diet and exercise training restore blood pressure and vasodilatory responses during physiological maneuvers in obese childrenCirculationYear: 20051111519152315837944 |
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Keywords: KEYWORDS: Prevention, Blood Pressure, Pre-hypertension, Genetics, Environment, Children. |
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