| Overweight men: clinical pregnancy after ART is decreased in IVF but not in ICSI cycles. | |
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MedLine Citation:
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PMID: 20635132 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate if elevated male body mass influences success after assisted reproductive technologies METHODS: Retrospective study of 290 cycles. RESULTS: Male body mass index greater than 25.0 kg/m² was associated with significantly lower clinical pregnancy (53.2% vs. 33.6%). Multivariable logistic regression indicated that the likelihood of clinical pregnancy was decreased if the male partner was overweight after in vitro fertilization but not after intracytoplasmic sperm injection (odds ratios: 0.21 [0.07-0.69] vs. 0.75 [0.38-1.49], respectively) after adjustment for number of embryos transferred, sperm concentration, female age and body mass. CONCLUSION: In this cohort, overweight status of the male partner was independently associated with decreased likelihood of clinical pregnancy after in vitro fertilization but not after intracytoplasmic sperm injection. A detrimental impact of higher male body mass was observed after adjusting for sperm concentration, suggesting that intracytoplasmic sperm injection may overcome some obesity related impairment of sperm-egg interaction. |
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Authors:
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Julia Keltz; Athena Zapantis; Sangita K Jindal; Harry J Lieman; Nanette Santoro; Alex J Polotsky |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2010-07-16 |
Journal Detail:
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Title: Journal of assisted reproduction and genetics Volume: 27 ISSN: 1573-7330 ISO Abbreviation: J. Assist. Reprod. Genet. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-10-28 Completed Date: 2011-02-04 Revised Date: 2013-05-29 |
Medline Journal Info:
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Nlm Unique ID: 9206495 Medline TA: J Assist Reprod Genet Country: Netherlands |
Other Details:
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Languages: eng Pagination: 539-44 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine, Bronx, NY, USA. julia.keltz@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Fertilization in Vitro* Humans Logistic Models Male Obesity* Odds Ratio Overweight* Pregnancy Retrospective Studies Sperm Injections, Intracytoplasmic* |
| Grant Support | |
ID/Acronym/Agency:
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K24 HD 41978/HD/NICHD NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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