Document Detail


Overweight men: clinical pregnancy after ART is decreased in IVF but not in ICSI cycles.
MedLine Citation:
PMID:  20635132     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate if elevated male body mass influences success after assisted reproductive technologies
METHODS: Retrospective study of 290 cycles.
RESULTS: Male body mass index greater than 25.0 kg/m² was associated with significantly lower clinical pregnancy (53.2% vs. 33.6%). Multivariable logistic regression indicated that the likelihood of clinical pregnancy was decreased if the male partner was overweight after in vitro fertilization but not after intracytoplasmic sperm injection (odds ratios: 0.21 [0.07-0.69] vs. 0.75 [0.38-1.49], respectively) after adjustment for number of embryos transferred, sperm concentration, female age and body mass.
CONCLUSION: In this cohort, overweight status of the male partner was independently associated with decreased likelihood of clinical pregnancy after in vitro fertilization but not after intracytoplasmic sperm injection. A detrimental impact of higher male body mass was observed after adjusting for sperm concentration, suggesting that intracytoplasmic sperm injection may overcome some obesity related impairment of sperm-egg interaction.
Authors:
Julia Keltz; Athena Zapantis; Sangita K Jindal; Harry J Lieman; Nanette Santoro; Alex J Polotsky
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-07-16
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  27     ISSN:  1573-7330     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-10-28     Completed Date:  2011-02-04     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  539-44     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine, Bronx, NY, USA. julia.keltz@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Female
Fertilization in Vitro*
Humans
Logistic Models
Male
Obesity*
Odds Ratio
Overweight*
Pregnancy
Retrospective Studies
Sperm Injections, Intracytoplasmic*
Grant Support
ID/Acronym/Agency:
K24 HD 41978/HD/NICHD NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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