Document Detail

Overview of physical-chemical methods for determining aminoglycoside antibiotics in tissues and fluids of food-producing animals.
MedLine Citation:
PMID:  4055615     Owner:  NLM     Status:  MEDLINE    
A survey of literature is presented dealing with physical-chemical methods for the detection and quantitation of aminoglycoside antibiotics (gentamicin, streptomycin, dihydrostreptomycin, and neomycin) that are used in food-producing animals. Recent developments in cleanup and determinative procedures, particularly liquid chromatography, for these compounds in fluids and tissues are emphasized. Little research has been done on residues in tissues compared with other biological matrices. This review also covers the chemistry, general characteristics, tolerances, and withdrawal times for the approved uses of these antibiotics in animals that are used for food.
B Shaikh; E H Allen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal - Association of Official Analytical Chemists     Volume:  68     ISSN:  0004-5756     ISO Abbreviation:  J Assoc Off Anal Chem     Publication Date:    1985 Sep-Oct
Date Detail:
Created Date:  1985-11-29     Completed Date:  1985-11-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7505559     Medline TA:  J Assoc Off Anal Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1007-13     Citation Subset:  IM    
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MeSH Terms
Aminoglycosides / analysis
Anti-Bacterial Agents / analysis*
Body Fluids / analysis*
Chemistry, Physical
Chromatography, Liquid
Chromatography, Thin Layer
Meat / analysis*
Physicochemical Phenomena
Spectrometry, Fluorescence
Reg. No./Substance:
0/Aminoglycosides; 0/Anti-Bacterial Agents

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