| Overview of nucleic acid arrays. | |
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MedLine Citation:
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PMID: 18265199 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nucleic acid array technology refers to the use and fabrication of arrays containing thousands of nucleic acid samples bound to solid substrates such as glass microscope slides or silicon wafers. Because the physical area occupied by each sample is usually 50 to 200 mum in diameter, it is possible to assay nucleic acid samples representing entire genomes, ranging in size from 3,000 to 32,000 genes, on a single slide. Microarrays are good for, among other things, analyzing gene expression patterns, genotyping and genetic mapping, comparative genomic hybridization, polysome analysis, and DNA-protein interactions. This overview describes the technology and the uses, and provides valuable web site listings for readers to obtain additional information. |
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Authors:
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J Derisi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] Volume: Chapter 22 ISSN: 1934-3647 ISO Abbreviation: Curr Protoc Mol Biol Publication Date: 2001 May |
Date Detail:
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Created Date: 2008-02-11 Completed Date: 2008-03-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8908160 Medline TA: Curr Protoc Mol Biol Country: United States |
Other Details:
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Languages: eng Pagination: Unit 22.1 Citation Subset: IM |
Affiliation:
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University of California, San Francisco, San Francisco, California, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chromosome Mapping DNA, Complementary / genetics Gene Expression Genotype Nucleic Acid Hybridization Oligonucleotide Array Sequence Analysis / methods* Oligonucleotide Probes Software Transcription, Genetic |
| Chemical | |
Reg. No./Substance:
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0/DNA, Complementary; 0/Oligonucleotide Probes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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