Document Detail


Overview and diagnosis of acute retinal necrosis syndrome.
MedLine Citation:
PMID:  18584564     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute retinal necrosis (ARN) syndrome, also known as Kirisawa's uveitis, is one of the most serious ocular diseases, and is characterized by a combination of peripheral, confluent, necrotizing retinitis, retinal arteritis, and intraocular inflammation. ARN syndrome is caused by the herpesvirus family, including herpes simplex virus (HSV) and varicella-zoster virus (VZV). The diagnosis of ARN syndrome is fundamentally based on clinical appearance and the demonstration of viral infection. Recently, polymerase chain reaction techniques permit detection of very small amounts of viral DNA in intraocular specimens. This knowledge can help in both the diagnosis and design of therapeutic strategy for ARN syndrome. Here we review the clinical presentation and the current advances in the diagnosis of ARN syndrome.
Authors:
Yoshihiko Usui; Hiroshi Goto
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in ophthalmology     Volume:  23     ISSN:  0882-0538     ISO Abbreviation:  Semin Ophthalmol     Publication Date:    2008 Jul-Aug
Date Detail:
Created Date:  2008-06-27     Completed Date:  2008-09-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610759     Medline TA:  Semin Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  275-83     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan. usuyoshi@aol.com
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MeSH Terms
Descriptor/Qualifier:
DNA, Viral / analysis
Diagnosis, Differential
Herpes Simplex / diagnosis*,  virology
Herpes Zoster / genetics
Herpes Zoster Ophthalmicus / diagnosis*,  virology
Humans
Polymerase Chain Reaction
Retinal Necrosis Syndrome, Acute / diagnosis*,  virology*
Simplexvirus / genetics
Chemical
Reg. No./Substance:
0/DNA, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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