| Overview of the cell cycle. | |
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MedLine Citation:
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PMID: 18228386 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Progression through the cell cycle is regulated by inductive signals from outside the cell and intracellular signal pathways, while the cycle itself is regulated by cyclin-dependent kinases (CDKs). An understanding of the functions of these molecules is necessary to understand the processes of mitosis, differentiation, senescence, apoptosis, and tumorigenesis. This overview reviews the current state of knowledge for the biology of the cell-cycle, the CDKs, the role of proteolysis, targets of the cell cycle machinery, and a paradigm of cell cycle analysis. |
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Authors:
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M S Park; A Koff |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] Volume: Chapter 8 ISSN: 1934-2616 ISO Abbreviation: Curr Protoc Cell Biol Publication Date: 2001 May |
Date Detail:
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Created Date: 2008-01-29 Completed Date: 2008-02-20 Revised Date: 2009-12-11 |
Medline Journal Info:
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Nlm Unique ID: 101287856 Medline TA: Curr Protoc Cell Biol Country: United States |
Other Details:
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Languages: eng Pagination: Unit 8.1 Citation Subset: IM |
Affiliation:
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Memorial Sloan-Kettering Cancer Center, New York, New York, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Cycle* / genetics, physiology Cell Cycle Proteins / physiology Cyclin-Dependent Kinase Inhibitor Proteins / physiology Cyclin-Dependent Kinases / physiology Cyclins / physiology DNA Replication Eukaryotic Cells / cytology Genes, cdc Humans Proteasome Endopeptidase Complex / physiology Retinoblastoma Protein / physiology Ubiquitin / physiology |
| Chemical | |
Reg. No./Substance:
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0/Cell Cycle Proteins; 0/Cyclin-Dependent Kinase Inhibitor Proteins; 0/Cyclins; 0/Retinoblastoma Protein; 0/Ubiquitin; EC 2.7.11.22/Cyclin-Dependent Kinases; EC 3.4.25.1/Proteasome Endopeptidase Complex |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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