| Overlap of symptom domains of separation anxiety disorder in adulthood with panic disorder-agoraphobia. | |
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MedLine Citation:
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PMID: 23247205 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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There is a need to explain the high level of comorbidity between separation anxiety disorder (SAD) in adulthood and panic disorder with agoraphobia (Pd-Ag). One possibility is that inadequate specification of symptom domains and/or diagnostic questions accounts for some of the comorbidity. The present anxiety clinic study examined responses of adult patients (n=646) with SAD and/or Pd-Ag on eight symptom domains based on a previous factor analysis of a commonly used separation anxiety measure, the ASA-27, as well as on the Anxiety Sensitivity Index. We also examined questionnaire items that did not load on the factor structure. All separation anxiety domains distinguished strongly between SAD and Pd-Ag. Comparisons across three groups (SAD alone, Pd-Ag alone and comorbid SAD/Pd-Ag) revealed that two symptom domains (anxiety about embarking on trips, and sleep disturbances) showed some overlap between Pd-Ag and SAD. Two of the items of the ASA-27 that did not load with other items in the factor analysis also showed overlap with Pd-Ag, with both referring to anxieties about leaving home. Patients with SAD (with or without Pd-Ag) returned higher scores on anxiety sensitivity than those with Pd-Ag alone. The findings support the distinctiveness of the construct of SAD and the capacity of the ASA-27 to discriminate between that disorder and Pd-Ag. SAD appears to be a more severe form of anxiety than Pd-Ag. There may be a need to refine items to include the reasons for avoiding leaving home, reluctance to sleep alone and to embark on trips, to ensure accurate discrimination between Pd-Ag and SAD in adulthood. |
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Authors:
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Derrick Silove; Claire Marnane |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-5 |
Journal Detail:
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Title: Journal of anxiety disorders Volume: 27 ISSN: 1873-7897 ISO Abbreviation: J Anxiety Disord Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-12-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8710131 Medline TA: J Anxiety Disord Country: - |
Other Details:
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Languages: ENG Pagination: 92-97 Citation Subset: - |
Copyright Information:
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Copyright © 2012 Elsevier Ltd. All rights reserved. |
Affiliation:
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School of Psychiatry, University of New South Wales, Randwick, Australia; Centre for Population Mental Health Research, Sydney South West Area Health Service, Liverpool, Australia. Electronic address: d.silove@unsw.edu.au. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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