Document Detail

Overestimation of final height prediction in patients with classical congenital adrenal hyperplasia using the Bayley and Pinneau method.
MedLine Citation:
PMID:  23155688     Owner:  NLM     Status:  In-Process    
BACKGROUND: A typical growth pattern with decreased pubertal growth spurt has been identified in patients with classical congenital adrenal hyperplasia (CAH).
OBJECTIVE: To evaluate the accuracy of final height predictions in patients with CAH using the Bayley and Pinneau (B&P) method.
PATIENTS AND METHODS: Using growth and final height data of 92 patients (57 F/35 M) with CAH due to 21-hydroxylase deficiency (38 SV/54 SW), final height predictions with the B&P method were compared to actual final heights.
RESULTS: In females, mean final height was 159.9 +/- 5.3 cm (-1.0 +/- 0.7 SDS) compared to predicted mean final height of 167.9 +/- 10.7 cm (+0.5 +/- 1.7 SDS), p < 0.001, overestimation 7.3 +/- 9.5 cm. In males, mean final height was 170.1 +/- 6 cm (-1.2 +/- 0.8 SDS) compared to predicted mean final height of 185.6 +/- 13.4 cm (+1.2 +/- 1.9 SDS), p < 0.001, overestimation 13.9 +/- 10.8 cm.
CONCLUSION: In classical CAH, final height prediction using the B&P method results in significant overestimation of final height.
Walter Bonfig; Hans Peter Schwarz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  25     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:  2012  
Date Detail:
Created Date:  2012-11-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  645-9     Citation Subset:  IM    
Division of Pediatric Endocrinology, Department of Pediatrics, Technische Universität München, Parzivalstr. 16, 0-80804 Munich, Germany.
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