| Overestimation of final height prediction in patients with classical congenital adrenal hyperplasia using the Bayley and Pinneau method. | |
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MedLine Citation:
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PMID: 23155688 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: A typical growth pattern with decreased pubertal growth spurt has been identified in patients with classical congenital adrenal hyperplasia (CAH). OBJECTIVE: To evaluate the accuracy of final height predictions in patients with CAH using the Bayley and Pinneau (B&P) method. PATIENTS AND METHODS: Using growth and final height data of 92 patients (57 F/35 M) with CAH due to 21-hydroxylase deficiency (38 SV/54 SW), final height predictions with the B&P method were compared to actual final heights. RESULTS: In females, mean final height was 159.9 +/- 5.3 cm (-1.0 +/- 0.7 SDS) compared to predicted mean final height of 167.9 +/- 10.7 cm (+0.5 +/- 1.7 SDS), p < 0.001, overestimation 7.3 +/- 9.5 cm. In males, mean final height was 170.1 +/- 6 cm (-1.2 +/- 0.8 SDS) compared to predicted mean final height of 185.6 +/- 13.4 cm (+1.2 +/- 1.9 SDS), p < 0.001, overestimation 13.9 +/- 10.8 cm. CONCLUSION: In classical CAH, final height prediction using the B&P method results in significant overestimation of final height. |
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Authors:
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Walter Bonfig; Hans Peter Schwarz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of pediatric endocrinology & metabolism : JPEM Volume: 25 ISSN: 0334-018X ISO Abbreviation: J. Pediatr. Endocrinol. Metab. Publication Date: 2012 |
Date Detail:
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Created Date: 2012-11-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9508900 Medline TA: J Pediatr Endocrinol Metab Country: Germany |
Other Details:
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Languages: eng Pagination: 645-9 Citation Subset: IM |
Affiliation:
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Division of Pediatric Endocrinology, Department of Pediatrics, Technische Universität München, Parzivalstr. 16, 0-80804 Munich, Germany. walter.bonfig@lrz.tum.de |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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