| Overestimation of Aerobic Capacity With the Bruce Treadmill Protocol in Patients Being Assessed for Suspected Myocardial Ischemia. | |
| | |
MedLine Citation:
|
PMID: 21427601 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
INTRODUCTION:: Peak oxygen uptake (Vo2) is prognostic for morbidity and mortality. Estimating aerobic capacity during traditional exercise stress testing is common as it has been shown that total treadmill time on the Bruce protocol predicts peak Vo2. However, the potential to overestimate peak Vo2 exists and may have clinical implications regarding the interpretation of exercise test data. METHODS:: Subjects (N = 303) with symptoms suggestive of myocardial ischemia underwent a myocardial perfusion study and an exercise test with simultaneous ventilatory expired gas analysis. Estimated peak Vo2 from the Bruce treadmill protocol was compared with measured peak Vo2. The Duke Treadmill Score (DTS) was calculated with treadmill time (DTStime) and also with measured Vo2 (DTSmeasured), expressed as metabolic equivalents (METs), and converted to time. RESULTS:: Peak measured METs was significantly lower than peak estimated METs in the entire cohort (6.5 ± 1.9 vs 8.8 ± 2.8, P < .001) as well as in female (5.7 ± 1.4 and 7.8 ± 2.1, P < .001) and male (7.3 ± 2.0 and 9.7 ± 3.1, P < .001) subgroups. Calculation of the DTS with measured METs resulted in a significantly lower score compared with its calculation with treadmill time (2.7 ± 3.5 vs 5.8 ± 4.6, P < .001). Receiver operating characteristic curve analysis revealed that DTSmeasured produce a statistically significant model for diagnosing a perfusion defect in both men and women (P < .05), whereas DTStime was diagnostic only in men (P < .05). CONCLUSION:: This study demonstrates that estimates of aerobic capacity are significantly higher than measured values and this difference may result in a significant underestimation of morbidity/mortality risk. |
| | |
Authors:
|
Sherry Pinkstaff; Mary Ann Peberdy; Michael C Kontos; Alexandre Fabiato; Sheryl Finucane |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-3-21 |
Journal Detail:
|
Title: Journal of cardiopulmonary rehabilitation and prevention Volume: - ISSN: 1932-751X ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-3-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101291247 Medline TA: J Cardiopulm Rehabil Prev Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Physical Therapy (Drs Pinkstaff and Finucane), Department of Physiology and Biophysics (Drs Pinkstaff and Fabiato), and Department of Internal Medicine (Drs Peberdy and Kontos), Medical College of Virginia Campus, Virginia Commonwealth University, Richmond; and Program in Physical Therapy (Dr Arena), University of New Mexico, Albuquerque. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Impact of Physical Activity, Cardiorespiratory Fitness, and Exercise Training on Markers of Inflamma...
Next Document: Do Antioxidant Vitamins Ameliorate the Beneficial Effects of Exercise Training on Insulin Sensitivit...