Document Detail

Overall prognosis of patients with diagnosed chronic organic solvent intoxication.
MedLine Citation:
PMID:  6298114     Owner:  NLM     Status:  MEDLINE    
The prognosis of 87 patients (mean age 38.6 years) was examined who had been diagnosed 3-9 years earlier as having chronic organic solvent intoxication due to trichloroethylene, perchloroethylene, or a mixture of solvents. The methods comprised an interview, a clinical neurological examination, neurophysiological examinations (EEGs and electroneuromyographs), and a psychological examination. In order to assess the prognosis, the patient's condition at the time of diagnosis was evaluated from the hospital records, and the condition upon reexamination was compared to that at the time of diagnosis. At the time of diagnosis, 31 patients had objective clinical signs in the neurological examination, whereas the remaining 56 had only subjective symptoms and neurophysiological or psychological findings attributed to the slight solvent intoxication. Upon reexamination, 42 patients had clinical neurological signs. Based on the clinical overall evaluation, the condition of 21 patients had deteriorated during the follow-up period, the condition of 23 had improved, and that of 43 had remained unchanged. The prognoses of the results of the separate examinations correlated poorly with each other. No statistically significant correlation was found between the overall prognosis and age, sex, the duration and the level of exposure, the termination of exposure after diagnosis, the presence of other diseases, or the use of alcohol.
M Antti-Poika
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International archives of occupational and environmental health     Volume:  51     ISSN:  0340-0131     ISO Abbreviation:  Int Arch Occup Environ Health     Publication Date:  1982  
Date Detail:
Created Date:  1983-04-21     Completed Date:  1983-04-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7512134     Medline TA:  Int Arch Occup Environ Health     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  127-38     Citation Subset:  IM    
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MeSH Terms
Central Nervous System Diseases / chemically induced
Chronic Disease
Middle Aged
Occupational Diseases / chemically induced*
Peripheral Nervous System Diseases / chemically induced
Socioeconomic Factors
Solvents / poisoning*
Tetrachloroethylene / poisoning
Trichloroethylene / poisoning
Reg. No./Substance:
0/Solvents; 127-18-4/Tetrachloroethylene; 79-01-6/Trichloroethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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