| Overall prognosis as the primary criterion of outcome in a clinical trial. | |
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MedLine Citation:
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PMID: 6641236 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a randomized trial on premature infants, with follow-up to 1 year of age only, the goal is to identify which one among the compared strategies of intervention affords the best outcome throughout life. This requires the assessment of lifetime prognosis at the end of follow-up as the primary criterion of outcome. Moreover, with the treatments potentially influencing a variety of organ systems, it is necessary to combine their separate prospects into an overall prognosis as a basis for identifying the preferable mode of intervention. The development of the scheme of rating overall prognosis posed considerable challenges, in theory as well as in application. |
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Authors:
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O S Miettinen; R C Ellison; G J Peckham; E N Kraybill; G L Breart; A S Nadas |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Controlled clinical trials Volume: 4 ISSN: 0197-2456 ISO Abbreviation: Control Clin Trials Publication Date: 1983 Sep |
Date Detail:
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Created Date: 1984-01-27 Completed Date: 1984-01-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006242 Medline TA: Control Clin Trials Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 227-37 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Clinical Trials as Topic* Ductus Arteriosus, Patent / physiopathology Humans Infant, Newborn Longevity Outcome and Process Assessment (Health Care) Prognosis* Quality of Life |
| Grant Support | |
ID/Acronym/Agency:
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HL23121/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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