Document Detail


Overall and minority-focused recruitment strategies in the PREMIER multicenter trial of lifestyle interventions for blood pressure control.
MedLine Citation:
PMID:  19879377     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recruitment strategies employed by four clinical centers across the US and a coordinating center were examined to identify successful overall and minority-focused recruitment strategies for the PREMIER multicenter trial of lifestyle changes for blood pressure control. The goal was to recruit 800 adults (40% African Americans) with systolic blood pressure of 120-159 mm Hg and diastolic of 80-95 mm Hg, not taking antihypertensive medication. Clinical centers used combinations of mass distribution of brochures, mass media, email distribution lists, screening events, and a national website. Culturally appropriate strategies for African Americans were designed by a Minority Implementation (MI) committee. Diversity training was provided for study staff, and African Americans were included in the study design process. Main recruitment outcomes were number overall and number of African Americans recruited by each strategy. Of the 810 randomized PREMIER participants, 279 (34%) were African American with site-specific percentages of 56%, 46%, 27%, and 8%. Of African Americans recruited, 151 (54%) were from mass distribution of brochures (mailed letter, flyer included in Val-Pak coupons, or other), 66 (24%) from mass media (printed article, radio, TV story or ads, 52 (19%) from word of mouth, and 10 (3%) from email/website and screening events combined. Yields for Non-Hispanic Whites were 364 (69%) from brochures, 71 (13%) from mass media, 49 (9%) from word of mouth and 47 (9%) from email/website and screening events. Mass distribution of brochures was relatively more effective with Non-Hispanic Whites, while African Americans responded relatively better to other recruitment strategies.
Authors:
Betty M Kennedy; Shiriki Kumanyika; Jamy D Ard; Patrice Reams; Cheryl A Johnson; Njeri Karanja; Jeanne B Charleston; Lawrence J Appel; Vallerie Maurice; David W Harsha
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2009-10-28
Journal Detail:
Title:  Contemporary clinical trials     Volume:  31     ISSN:  1559-2030     ISO Abbreviation:  Contemp Clin Trials     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-04     Completed Date:  2010-05-04     Revised Date:  2014-09-15    
Medline Journal Info:
Nlm Unique ID:  101242342     Medline TA:  Contemp Clin Trials     Country:  United States    
Other Details:
Languages:  eng     Pagination:  49-54     Citation Subset:  IM    
Copyright Information:
Published by Elsevier Inc.
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MeSH Terms
Descriptor/Qualifier:
Adult
African Americans*
Cultural Competency
European Continental Ancestry Group*
Female
Humans
Hypertension / ethnology*,  therapy*
Life Style / ethnology*
Male
Middle Aged
Minority Groups*
Multicenter Studies as Topic*
Patient Selection*
Pilot Projects
Grant Support
ID/Acronym/Agency:
M01 RR00052/RR/NCRR NIH HHS; U01 HL060570/HL/NHLBI NIH HHS; U01 HL060570-02/HL/NHLBI NIH HHS; U01 HL060571-03/HL/NHLBI NIH HHS; U01 HL060573/HL/NHLBI NIH HHS; U01 HL060573-04/HL/NHLBI NIH HHS; U01 HL060574-05/HL/NHLBI NIH HHS; U01 HL062828-02/HL/NHLBI NIH HHS; U01 HL60570/HL/NHLBI NIH HHS; U01 HL60571/HL/NHLBI NIH HHS; U01 HL60573/HL/NHLBI NIH HHS; U01 HL60574/HL/NHLBI NIH HHS; U01 HL62828/HL/NHLBI NIH HHS
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