Document Detail


Overactive bladder syndrome: considerations in pharmacotherapy and new perspectives.
MedLine Citation:
PMID:  15925039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The great epidemiological relevance of the overactive bladder (OAB) syndrome and its impact on quality of life of sufferers has encouraged a growing amount of research both in basic science and in clinical fields, with the pharmacological treatment of OAB syndrome being particularly investigated. Recently a new perspective for the use of alpha-lytic drugs in the treatment of OAB syndrome has been disclosed due to encouraging anecdotal data, and to the identification of different adrenoceptor subtypes in the female lower urinary tract. Starting with a reference picture of female lower urinary tract disorders, the authors review the present pharmacological treatment of female lower urinary tract disorders, and delineate the new perspectives acquired from recent studies of adrenoceptor subtypes.
Authors:
Stefano Salvatore; Marco Soligo; Fabio Proietti; Stefania Citterio; Walter Artibani; Rodolfo Milani
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Publication Detail:
Type:  Journal Article; Review     Date:  2005-01-15
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  120     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-31     Completed Date:  2005-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  129-33     Citation Subset:  IM    
Affiliation:
Department of Gynaecologic Surgery, Bassini Hospital, University of Milan, Bicocca, Via Ciro Menotti 76, 21100 Varese, Italy. stefanosalvatore@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adrenergic alpha-Antagonists / therapeutic use
Cholinergic Antagonists / therapeutic use
Estrogen Replacement Therapy
Female
Humans
Imipramine / therapeutic use
Male
Menopause
Muscle Contraction / drug effects
Muscle, Smooth
Urinary Incontinence / drug therapy*
Chemical
Reg. No./Substance:
0/Adrenergic alpha-Antagonists; 0/Cholinergic Antagonists; 50-49-7/Imipramine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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