Document Detail


Ovarian stromal vascularity is not predictive of ovarian response and pregnancy.
MedLine Citation:
PMID:  16454933     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The role of ovarian stromal vascularity in the prediction of the ovarian response and pregnancy in infertile women was evaluated by comparing age of women, body mass index (BMI), basal FSH concentration, antral follicle count (AFC) and ovarian stromal vascularity indices measured by three-dimensional power Doppler ultrasound. A total of 111 women in their first IVF cycle were analysed. They were aged <40 years with basal FSH concentration <10 IU/l on recruitment for IVF treatment. AFC, mean ovarian volume and mean ovarian 3D power Doppler flow indices were determined on day 2 of the treatment cycle prior to a standard regimen of ovarian stimulation. Ovarian response was represented by the number of oocytes, serum oestradiol, the duration and dosage of gonadotrophins. AFC achieved the best predictive value in relation to the number of oocytes obtained, followed by age of women and BMI. Basal FSH concentration was the only predictive factor for the duration and dosage of gonadotrophin used. Mean ovarian 3D power Doppler flow indices were not predictive of pregnancy in a multiple logistic regression analysis. Ovarian 3D power Doppler flow indices measured after pituitary down-regulation were not predictive of the ovarian response and pregnancy in the IVF treatment.
Authors:
Ernest Hung Yu Ng; Oi Shan Tang; Carina Chi Wai Chan; Pak Chung Ho
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  12     ISSN:  1472-6483     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-02-03     Completed Date:  2006-09-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  43-9     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China. nghye@hkucc.hku.hk
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Body Mass Index
Estradiol / blood
Female
Fertilization in Vitro*
Follicle Stimulating Hormone / blood
Humans
Infertility / therapy*
Logistic Models
Ovarian Follicle / physiology*
Ovary / blood supply*,  physiology,  ultrasonography
Pregnancy
Treatment Outcome
Ultrasonography, Doppler
Chemical
Reg. No./Substance:
50-28-2/Estradiol; 9002-68-0/Follicle Stimulating Hormone

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