Document Detail


Ovarian hyperstimulation syndrome prevention strategies: in vitro maturation.
MedLine Citation:
PMID:  21157982     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The only reliable way to eliminate the risk of ovarian hyperstimulation syndrome (OHSS) is complete avoidance of gonadotropin ovarian stimulation. It could be argued that in vitro maturation (IVM) of oocytes represents the most effective strategy to prevent OHSS. IVM has been an established treatment option in many centers worldwide for over a decade. The use of IVM and natural cycle in vitro fertilization (IVF) combined with IVM can result in clinical pregnancy rates that compare to those obtained with conventional IVF. The obstetric and perinatal outcomes of IVM pregnancies are similar to those conceived from stimulated IVF or spontaneous conceptions. To date, more than a thousand healthy infants have been born without an increase in fetal abnormalities. Although IVM may not replace standard IVF, it plays an increasingly important role in assisted reproductive technology, especially in the settings of high responders and those patients at risk of OHSS.
Authors:
Jack Y J Huang; Ri-Cheng Chian; Seang Lin Tan
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in reproductive medicine     Volume:  28     ISSN:  1526-4564     ISO Abbreviation:  Semin. Reprod. Med.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-12-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100909394     Medline TA:  Semin Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  519-31     Citation Subset:  IM    
Copyright Information:
© Thieme Medical Publishers.
Affiliation:
The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, New York, New York 10021, USA. jyh9005@med.cornell.edu
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