Document Detail

Ovarian hyperstimulation syndrome may be more likely if multiple pregnancy occurs following assisted conception.
MedLine Citation:
PMID:  8739735     Owner:  NLM     Status:  MEDLINE    
Whereas modern assisted conception with such techniques as in vitro fertilisation now helps many subfertile couples to fulfill their ambition to have a child, it has not been without a price. The increased incidence of multiple pregnancies, with their attendant maternal and perinatal sequelae following assisted conception is well known, but perinatologists may be far less familiar with the Ovarian Hyperstimulation Syndrome (OHSS) which is the other major complication when controlled ovarian hyperstimulation is used during assisted conception treatment. Mild forms of OHSS are common and require no more than symptomatic treatment. Severe forms of OHSS are uncommon occurring in 0.6% to 14% of IVF cycles, but are nonetheless very important to identify as they may lead to thrombo-embolic disease, cardiorespiratory dysfunction, renal failure and even death [6]. This review considers whether OHSS may be related to multiple pregnancy by reviewing the available literature and local experience.
R S Mathur; L A Joels; J M Jenkins
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta geneticae medicae et gemellologiae     Volume:  44     ISSN:  0001-5660     ISO Abbreviation:  Acta Genet Med Gemellol (Roma)     Publication Date:  1995  
Date Detail:
Created Date:  1996-10-23     Completed Date:  1996-10-23     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0370314     Medline TA:  Acta Genet Med Gemellol (Roma)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  233-5     Citation Subset:  IM    
University of Bristol, Department of Obstetrics & Gynaecology, St. Michael's Hospital, Bristol.
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MeSH Terms
Fertilization in Vitro*
Ovarian Hyperstimulation Syndrome / etiology*
Pregnancy, Multiple*

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