Document Detail


Ovarian cryopreservation.
MedLine Citation:
PMID:  22278067     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Cryopreservation of ovarian tissue and future autotransplantation are new promising strategies for fertility preservation in various malignant and non-malignant diseases facing the risk of ovarian failure. Ovarian cortrical tissue pieces or intact whole ovary can be removed by laparoscopy without any significant delay in chemotherapy. Slow freezing and vitrification methods are developed to avoid damage to follicles. Ovarian tissue can be transplanted in an orthotopic or heterotopic location when the patient is cured from the disease. Autotransplantation can be performed if absence of malignant cells in the graft is confirmed. Although the procedures are still experimental, ovarian cryopreservation is the single option in prepubertal girls who have not sexual maturity. Earlier team approach of oncologists and reproductive endocrinologists may provide a more successful and professional way of fertility preservation.
Authors:
K Jeong; E Aslan; E Ozkaya; M Sonmezer; K Oktay
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Minerva medica     Volume:  103     ISSN:  0026-4806     ISO Abbreviation:  Minerva Med.     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400732     Medline TA:  Minerva Med     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  37-46     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, School of Medicine, Ewha Womans University, Seoul, Korea - koktay@fertilitypreservation.org.
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