Document Detail

Ovarian cryopreservation: experimental or established and a cure for the menopause?
MedLine Citation:
PMID:  22858254     Owner:  NLM     Status:  MEDLINE    
Long-term (>7 years) duration of function of ovarian cortical tissue grafts in three patients who have had several successful pregnancies is encouraging and requires us to carefully examine the risk benefit analysis of this technique for our future patients. However, the success rate for ovarian cryopreservation is unclear as the denominator (the number of women in whom frozen-thawed ovarian tissue has been re-implanted) is unknown. There still remain many unknowns and much more research is required before ovarian transplantation can be considered standard practice. The ability of ovarian cryopreservation to preserve fertility for some young survivors of cancer is proven, but the indications for which patients should be offered this exciting new technology are not yet established.
W H Wallace; T W Kelsey; R A Anderson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  25     ISSN:  1472-6491     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-08-03     Completed Date:  2012-12-26     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  93-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
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MeSH Terms
Cryopreservation / methods*
Infertility, Female / etiology,  therapy*
Neoplasms / radiotherapy*
Ovary / transplantation*
Radiotherapy / adverse effects*
Reproductive Techniques, Assisted*
Risk Assessment
Time Factors
Grant Support
G1100357//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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