Document Detail


Ovarian choriocarcinoma arising from partial mole as evidenced by deoxyribonucleic acid microsatellite analysis.
MedLine Citation:
PMID:  14672475     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Recent developments in genetic analysis allow determination of the origin of choriocarcinoma (ie, gestational or nongestational), which helps determine the strategy for clinical treatment of the disease. CASE: We present a case of ovarian choriocarcinoma forming a huge ovarian mass 40 days after the patient's last menstrual period. Deoxyribonucleic acid microsatellite analysis of the tumor revealed that it contained a single maternal and two paternal alleles at several independent loci, consistent with the tumor resulting from ovarian pregnancy of a partial hydatidiform mole. CONCLUSION: This is the first description of an ovarian pregnancy of a partial hydatidiform mole-derived ovarian choriocarcinoma.
Authors:
Akira Namba; Shunsuke Nakagawa; Naohito Nakamura; Yutaka Takazawa; Koji Kugu; Osamu Tsutsumi; Yuji Taketani
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  102     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-12-15     Completed Date:  2004-01-09     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  991-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Alleles
Choriocarcinoma / complications*,  genetics,  pathology,  surgery
Diagnosis, Differential
Female
Humans
Hydatidiform Mole / diagnosis*,  etiology,  pathology,  surgery
Magnetic Resonance Imaging
Microsatellite Repeats
Ovarian Neoplasms / complications*,  genetics,  pathology,  surgery
Parity
Pregnancy
Uterine Neoplasms / diagnosis*,  etiology,  pathology,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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