| Ovarian cancer: comparison of observer performance for four methods of interpreting CT scans. | |
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MedLine Citation:
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PMID: 10429697 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To assess the effects of four interpretative methods on observers' mean sensitivity and specificity by using computed tomography (CT) of ovarian carcinoma as a model. MATERIALS AND METHODS: CT scans in 98 patients with ovarian carcinoma and 49 women who were disease free were retrospectively reviewed by four experienced blinded radiologists to compare single-observer reading, single-observer reading with an anatomic checklist, paired-observer reading (simultaneous double reading), and replicated reading (combination of two independent readings). Confidence level scoring was used to identify three possible disease forms in each patient: extranodal tumor, lymphadenopathy, and ascites. Patient conditions were then categorized as abnormal or normal. RESULTS: There were no significant improvements in sensitivity or specificity for classification of patient conditions as abnormal or normal when comparing single-observer interpretation with single-observer interpretation with a checklist or paired-observer interpretation. Although there was no significant improvement in the mean sensitivity (93% vs 94%) by using the replicated reading method, there was a statistically significant improvement in mean specificity (85% vs 79%) for the replicated readings compared with single-observer interpretations (P < .05). CONCLUSION: Diagnostic aids such as checklists and paired simultaneous readings did not lead to an improved mean observer performance for experienced readers. However, an increase in the mean specificity occurred with replicated readings. |
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Authors:
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P J Fultz; C V Jacobs; W J Hall; R Gottlieb; D Rubens; S M Totterman; S Meyers; C Angel; G Del Priore; D P Warshal; K H Zou; D E Shapiro |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Radiology Volume: 212 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1999 Aug |
Date Detail:
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Created Date: 1999-08-17 Completed Date: 1999-08-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 401-10 Citation Subset: AIM; IM |
Affiliation:
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Dept of Radiology, University of Rochester Medical Center, NY 14642, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Humans Middle Aged Observer Variation Ovarian Neoplasms / epidemiology, radiography* ROC Curve Retrospective Studies Sensitivity and Specificity Tomography, X-Ray Computed* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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