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Ovarian cancer as a genetic disease .
MedLine Citation:
PMID:  23276941     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Ovarian cancer is characterized by the highest mortality rate among gynecologic malignancies. Therefore, there is a growing need for innovative therapies and techniques for monitoring and prevention of this disease. The exact cause of most ovarian tumors usually remains unknown. Ovarian cancer is believed to be caused by a range of different variables. This review is an attempt to summarize some genetic factors involved in the disruption of certain signaling pathways responsible for ovarian tumor transformation and development. Those factors considerably contribute to accurate diagnostics, treatment and prognosis in ovarian cancer.
Authors:
Agnieszka Lech; Teodora Daneva; Shina Pashova; Hristo Gagov; Robert Crayton; Wojciech Kukwa; Anna M Czarnecka; Cezary Szczylik
Publication Detail:
Type:  Journal Article     Date:  2013-01-01
Journal Detail:
Title:  Frontiers in bioscience : a journal and virtual library     Volume:  18     ISSN:  1093-4715     ISO Abbreviation:  Front. Biosci.     Publication Date:  2013  
Date Detail:
Created Date:  2013-01-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9709506     Medline TA:  Front Biosci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  543-63     Citation Subset:  IM    
Affiliation:
Department of Oncology, Military Institute of Medicine, Szaserow 128, 04-141 Warsaw, Poland.
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