| Outpatient use of oral rehydration solutions in Apache population: effect of instructions on preparation and contamination. | |
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MedLine Citation:
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PMID: 6389814 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Oral Rehydration Solutions (ORS) containing 90 and 50 mmol/L sodium have recently been recommended for use in ambulatory children in the U.S. These solutions are now marketed in powder form by some commercial companies. However, few data are available in the U.S. on the accuracy with which the solutions are mixed at home or on the bacterial contamination that may occur during mixing. We evaluated the effect of various forms of instructions on the occurrence of bacterial contamination and accuracy of mixing ORS at home by mothers of patients who were dispensed the dry ingredients of an ORS containing 90 mmol/L sodium at the U.S. Public Health Service Hospital, Whiteriver, Arizona. Patients were randomized to one of the four following groups: group I (23 patients) was given written instructions for mixing the solution along with a pre-marked container; group II (22 patients) was given written instructions only; group III (22 patients) was given a premarked container only; and group IV (19 patients) was given neither. All patients were given oral instructions in the preparation of ORS and were asked to refrigerate the reconstituted ORS. We collected samples of ORS at the patient's home 1 day after the clinic visit, to measure their electrolyte content and to identify any bacterial contamination. Mean Na+ concentrations were significantly lower in the ORS prepared by mothers/guardians in groups that were not given a premarked container [82 +/- 13 (II) and 79 +/- 21 (IV) mmol/L vs. 88 +/- 13 (I) and 92 +/- 14 (III) mmol/L; p less than 0.01].(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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M Santosham; S Foster; S Garrett; L Croll; S Evans; W M Spira; R E Black |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of pediatric gastroenterology and nutrition Volume: 3 ISSN: 0277-2116 ISO Abbreviation: J. Pediatr. Gastroenterol. Nutr. Publication Date: 1984 Nov |
Date Detail:
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Created Date: 1985-01-15 Completed Date: 1985-01-15 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8211545 Medline TA: J Pediatr Gastroenterol Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 687-91 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Ambulatory Care* Arizona Child Diarrhea / therapy Drug Contamination Electrolytes / administration & dosage* Escherichia coli / growth & development Female Fluid Therapy* / methods Humans Indians, North American* Infant Sodium / administration & dosage Solutions Water Supply / adverse effects* |
| Grant Support | |
ID/Acronym/Agency:
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N01-AI02660/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Electrolytes; 0/ORALIT; 0/Solutions; 7440-23-5/Sodium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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